释义 |
DictionarySeemutationsuppressor mutation
suppressor mutation[sə′pres·ər myü‚tā·shən] (genetics) A mutation that restores the function lost after a primary mutation at a different locus. suppressor mutation
mutation [mu-ta´shun] 1. a permanent transmissible change in the genetic material.2. an individual exhibiting such a change.point mutation a mutation resulting from a change in a single base pair in the DNA molecule.somatic mutation a genetic mutation occurring in a somatic cell, providing the basis for mosaicism.suppressor mutation the correction of the effect of a mutation at one locus by a mutation at another locus.sup·pres·sor mu·ta·tion1. a second mutation that alters the anticodon in a tRNA so that it can recognize a nonsense (stop) codon, thus suppressing termination of the amino acid chain. Compare: amber mutation, ochre mutation, umber mutation. 2. genetic changes such that the effect of a m. in one place can be masked by a second m. in another location. There are two types: intergenic suppression (occurring in a different gene) and intragenic suppression (occurring in the same gene but at a different site). Synonym(s): nonsense mutationsup·pres·sor mu·ta·tion (sŭ-pres'ŏr myū-tā'shŭn) 1. A mutation that alters the anticodon in a tRNA so that it is complementary to a termination codon, thus suppressing termination of the amino acid chain. 2. Genetic changes such that the effect of a mutation in one place can be overcome by a second mutation in another location. There are two types: intergenic suppression (occurring in a different gene) and intragenic suppression (occurring in the same gene but at a different site). suppressor mutation a MUTATION that acts to restore the normal functioning of another gene located elsewhere in the GENOME (intergenic suppression), or another mutation at a different site in the same gene (intragenic suppression).LegalSeeMutation |