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单词 vaccine
释义

vaccine


vac·cine

V0002500 (văk-sēn′, văk′sēn′)n.1. a. A preparation of a weakened or killed pathogen, such as a bacterium or virus, or of a portion of the pathogen's structure, that is administered to prevent or treat infection by the pathogen and that functions by stimulating the production of an immune response.b. A preparation from the cowpox virus that protects against smallpox when administered to an individual.2. Computers A software program designed to detect and stop the progress of computer viruses.
[From Latin vaccīnus, of cows, from vacca, cow.]

vaccine

(ˈvæksiːn) n1. (Medicine) a suspension of dead, attenuated, or otherwise modified microorganisms (viruses, bacteria, or rickettsiae) for inoculation to produce immunity to a disease by stimulating the production of antibodies2. (Medicine) (originally) a preparation of the virus of cowpox taken from infected cows and inoculated in humans to produce immunity to smallpox3. (Medicine) (modifier) of or relating to vaccination or vaccinia4. (Computer Science) computing a piece of software designed to detect and remove computer viruses from a system[C18: from New Latin variolae vaccīnae cowpox, title of medical treatise (1798) by Edward Jenner, from Latin vacca a cow]

vac•cine

(vækˈsin; esp. Brit. ˈvæk sin)

n. 1. any preparation of weakened or killed bacteria or viruses introduced into the body to prevent a disease by stimulating antibodies against it. 2. the virus of cowpox, used in vaccination, obtained from pox vesicles of a cow or person. 3. a software program that helps to protect against computer viruses. [1800–05; < New Latin (variolae)vaccīnae cowpox =vacc(a) cow + -īnae, feminine pl. of -īnus -ine1]

vac·cine

(văk-sēn′) A substance that stimulates cells in the immune system to recognize and attack disease-causing agents, especially through the production of antibodies. Most vaccines are given by injection or are swallowed as liquids. Vaccines may contain a weaker form of the disease-causing virus or bacterium or even a DNA fragment or some other component of the agent. See Note at Jenner.Did You Know? In the 1950s, polio epidemics left thousands of children with permanent physical disabilities. Today, kids are given a polio vaccine to keep them from catching the virus. That vaccine, like most others, works by stimulating the body's immune system to produce antibodies—substances that defend the body against infection by recognizing and destroying disease-causing agents like viruses and bacteria. Scientists usually prepare vaccines by taking a sample of the disease-causing agent and weakening it with heat or chemicals. That way, the agent loses its ability to cause serious illness but is still able to stimulate the body to produce antibodies and provide immunity. But finding safe vaccines that are also effective is a challenge. Today, scientists are able to change the structure of viruses and bacteria at the level of their DNA. They remove the most harmful fragments of DNA and then use what is left in vaccines. New vaccines containing harmless bits of DNA from disease-causing germs have also been developed—all to make diseases like polio a thing of the past.
Thesaurus
Noun1.vaccine - immunogen consisting of a suspension of weakened or dead pathogenic cells injected in order to stimulate the production of antibodiesvaccine - immunogen consisting of a suspension of weakened or dead pathogenic cells injected in order to stimulate the production of antibodiesvaccinumDPT vaccine - abbreviation for combination vaccine against diphtheria and pertussis (whooping cough) and tetanus toxoids; usually given in a series of injections in early childhoodimmunizing agent, immunogen - any substance or organism that provokes an immune response (produces immunity) when introduced into the bodypneumococcal vaccine, Pneumovax - vaccine (trade name Pneumovax) effective against the 23 most common strains of pneumococcuspoliovirus vaccine - vaccine prepared from poliovirus to provide immunity to poliomyelitisproteosome, proteosome vaccine - a form of vaccine that can be administered by an inhaler

vaccine

noun inoculation, injection, immunization Anti-malarial vaccines are now undergoing trials.
Translations
疫苗

vaccine

(ˈvӕksiːn) noun a substance made from the germs that cause a particular disease, especially smallpox, and given to a person or animal to prevent him from catching that disease. (尤指牛痘)疫苗 (尤指牛痘)疫苗 ˈvaccinate (-ksi-) verb to protect (a person etc) against a disease by putting vaccine into his blood. Has your child been vaccinated against smallpox? (某人)接種疫苗,打預防針 接种疫苗,注射疫苗 ˌvacciˈnation (-ksi-) noun (an) act of vaccinating or process of being vaccinated. I'm to have a vaccination tomorrow; Vaccination was introduced in the eighteenth century. 疫苗接種 种痘

vaccine


vaccine:

see vaccinationvaccination,
means of producing immunity against pathogens, such as viruses and bacteria, by the introduction of live, killed, or altered antigens that stimulate the body to produce antibodies against more dangerous forms.
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.

Vaccine

 

a preparation obtained from microorganisms (bacteria, rickettsias, viruses) or products of their activity and used for active immunization of human beings and animals for prophylactic and therapeutic purposes. Vaccine was first used in 1796 by the English physician E. Jenner, who inoculated persons with cowpox, or vaccinia (hence the name “vaccine”) to protect them against smallpox.

Live, killed, and chemical vaccines and toxoids are distinguished.

Live vaccines are made from specially attenuated cultures of microorganisms deprived of their capacity to cause disease but remaining capable of reproducing in the body and causing immunity. The first to create live vaccines against anthrax (1881) and rabies (1885) was the French microbiologist L. Pasteur. The live tuberculosis vaccine (BCG) proposed in 1926 by the French scientists A. Calmette and C. Guérin won universal recognition; it greatly reduced the tuberculosis rate. Many live vaccines were created by Soviet scientists: for example, typhus vaccine (P. F. Zdrodovskii, 1957-59), influenza vaccine (A. A. Smorodintsev, V. D. Solov’ev, and V. M. Zhdanov, 1960), brucellosis vaccine (P. A. Vershilova, 1947-51), and smallpox vaccine (M. A. Morozov, 1941-60). Vaccines are the only effective inoculative preparations for certain diseases (rabies, smallpox, plague, tularemia). Live vaccines generally produce long-lasting immunity.

Killed vaccines are made from microorganisms killed by physical methods (heating) or chemical methods (phenol, formaldehyde, acetone). Killed vaccines are used to prevent only those diseases for which live vaccines are not available (typhoid, paratyphoid B, whooping cough, cholera, tick-borne encephalitis). They provide less protection than live vaccines. Hence immunity develops only after a course of immunization (vaccination) consisting of several inoculations.

Chemical vaccines are substances isolated from bacterial cells by various chemical methods and containing the main elements that cause immunity. Chemical vaccines against intestinal infections were first employed in 1941 as part of the NIISI polyvalent vaccine proposed by the Soviet scientists N. I. Aleksandrov and N. E. Gefen. Chemical vaccines are used to provide protection against paratyphoid B, typhoid, and rickettsial diseases.

The development of immunity following the injection of toxoids results from the appearance in the blood of antibodies that neutralize the effect of a particular toxin. Toxoids were obtained for the first time during the years 1923-26 by the French scientist G. Ramon. Toxoids are used to prevent diphtheria, tetanus, botulism, gas gangrene, and staphylococcal infections.

Vaccines can be made from the causative agent of a single infection, so-called monovalent vaccines, or from a combination of two or more causative agents, polyvalent vaccines. The latter produce immunity to several infectious diseases.

There are various methods of administering vaccines. In the case of live vaccines, they are related to a certain extent to the routes by which the causative agents enter the body. Thus, poliomyelitis vaccine is administered orally; influenza vaccine intranasally; smallpox, anthrax, and tularemia vaccines epidermally; brucellosis vaccine intradermally; typhus vaccine subcutaneously. Killed vaccines and toxoids are injected subcutaneously or intramuscularly.

Live vaccine is used to treat rabies (vaccine therapy), the only method of protecting man from this fatal disease. Autovaccines are used to treat several chronic inflammatory diseases caused by staphylococci and streptococci.

In the USSR, vaccines are produced by scientific production institutions. The quality of the preparations is controlled by the L. A. Tarasevich State Control Institute for Biomedical Preparations in Moscow.

A. KH. KANCHURIN

Vaccines in veterinary medicine. The principles used in preparing and classifying vaccines for the treatment of animal diseases are the same as those for human diseases. The most widely used live vaccines in veterinary practice include anthrax vaccines—STI and GNKI; swine erysipelas vaccine —from the Konev strain and VR2; brucellosis vaccine— from strain 19; and vaccines against cholera, smallpox, and Newcastle disease. Killed vaccines are used to prevent and treat more than 20 infectious diseases of animals.

REFERENCES

Ramon, G. Sorok let issledovatel’skoi raboty. Moscow, 1962. (Translated from French.)
Vygodchikov, G. V. “Nauchnye osnovy vaktsinno-syvorotochnogo dela.” In Mnogotomnoe rukovodstvo po mikrobiologii, klinike i epidemiologii infektsionnykh boleznei, vol. 3. Moscow, 1964. Pages 485-506.
Kravchenko, A. T., R. A. Saltykov, and F. F. Rezepov. Prakticheskoe rukovodstvo po primeneniiu biologic he skikh preparatov. Moscow, 1968.

A. KH. KANCHURIN
and S. G. KOLESOV

vaccine

[vak′sēn] (immunology) A suspension of killed or attenuated bacteria or viruses or fractions thereof, injected to produce active immunity.

vaccine

Med1. a suspension of dead, attenuated, or otherwise modified microorganisms (viruses, bacteria, or rickettsiae) for inoculation to produce immunity to a disease by stimulating the production of antibodies 2. (originally) a preparation of the virus of cowpox taken from infected cows and inoculated in humans to produce immunity to smallpox 3. of or relating to vaccination or vaccinia 4. Computing a piece of software designed to detect and remove computer viruses from a system

vaccine


vaccine

 [vak-sēn´] a suspension of attenuated or killed microorganisms (viruses, bacteria, or rickettsiae), administered for prevention, amelioration, or treatment of infectious diseases.anthrax vaccine a cell-free protein extract of cultures of Bacillus anthracis, used for immunization against anthrax.attenuated vaccine a vaccine prepared from live microorganisms or viruses cultured under adverse conditions, leading to loss of their virulence but retention of their ability to induce protective immunity.autogenous vaccine a vaccine prepared from microorganisms which have been freshly isolated from the lesion of the patient who is to be treated with it.bacterial vaccine a preparation of killed or attenuated bacteria used as an active immunizing agent.BCG vaccine see bcg vaccine.cholera vaccine a preparation of killed Vibrio cholerae, administered intradermally, subcutaneously, or intramuscularly for immunization against cholera.diphtheria and tetanus toxoids and pertussis vaccine DTP vaccine: a combination of diphtheria and tetanus toxoids and pertussis vaccine; administered intramuscularly for simultaneous immunization against diphtheria, tetanus, and whooping cough. When the pertussis vaccine is an acellular form, the combination may be abbreviated DTaP.diphtheria and tetanus toxoids and pertussis vaccine adsorbed and Haemophilus b conjugate vaccine a combination of toxoid" >diphtheria toxoid, toxoid" >tetanus toxoid, pertussis vaccine, and Haemophilus b conjugate vaccine; administered intramuscularly to children 18 months to 5 years of age for simultaneous immunization against diphtheria, tetanus, cough" >whooping cough, and infection by Haemophilus influenzae type b.DTP vaccine diphtheria and tetanus toxoids and pertussis vaccine.Haemophilus b conjugate vaccine (HbCV) a preparation of Haemophilus influenzae type b capsular polysaccharide covalently bound to diphtheria toxoid or to a specific diphtheria protein, meningococcal protein, or tetanus protein; it stimulates both B and T lymphocyte responses and is much more immunogenic than the polysaccharide vaccine. Administered intramuscularly as a routine immunizing agent in infants and young children.Haemophilus b polysaccharide vaccine (HbPV) a preparation of highly purified capsular polysaccharide derived from Haemophilus influenzae type b, which stimulates an immune response in B lymphocytes only; administered intramuscularly or subcutaneously as an immunizing agent in children ages 18 months to 5 years.hepatitis A vaccine inactivated an inactivated whole virus vaccine derived from an attenuated strain of hepatitis A virus grown in cell culture; administered intramuscularly.hepatitis B vaccine a preparation of hepatitis B surface antigen, derived either from human plasma of carriers of hepatitis B (hepatitis B vaccine inactivated) or from cloning in yeast cells (hepatitis B vaccine [recombinant]); administered intramuscularly.heterologous vaccine a vaccine that confers protective immunity against a pathogen that shares cross-reacting antigens with the microorganisms in the vaccine.human diploid cell vaccine rabies vaccine prepared from rabies virus grown in cultures of human diploid embryo lung cells and inactivated; administered intramuscularly or intradermally.influenza virus vaccine a killed virus vaccine used in immunization against influenza; it is trivalent, usually containing two influenza A virus strains and one influenza B virus strain.live vaccine a vaccine prepared from live microorganisms that have been attenuated but retain their immunogenic properties.Lyme disease vaccine (recombinant OspA) a preparation of outer surface protein A (OspA), a cell surface lipoprotein of Borrelia burgdorferi, produced by recombinant technology; administered intramuscularly for active immunization against lyme disease.measles, mumps, and rubella virus vaccine live (MMR) a combination of live attenuated measles, mumps, and rubella viruses, administered subcutaneously for simultaneous immunization against measles, mumps, and rubella.measles and rubella virus vaccine live a combination of live attenuated measles and rubella viruses, administered subcutaneously for simultaneous immunization against measles and rubella.measles virus vaccine live a live attenuated virus vaccine used for immunization against measles, although it is usually administered as the combination vaccine" >measles, mumps, and rubella virus vaccine.meningococcal polysaccharide vaccine a preparation of a capsular antigen of Neisseria meningitidis, administered subcutaneously to provide immunity to meningitis.mumps virus vaccine live a live attenuated virus vaccine used in immunization against mumps; usually administered as the combination vaccine" >measles, mumps, and rubella virus vaccine.pertussis vaccine a preparation of killed Bordetella pertussis bacilli (whole-cell vaccine) or of purified antigenic components thereof (acellular vaccine), used to immunize against pertussis; generally used in combination with diphtheria and tetanus toxoids (DTP or DTaP).plague vaccine a preparation of killed Yersinia pestis bacilli, administered intramuscularly as an active immunizing agent against plague.pneumococcal heptavalent conjugate vaccine a preparation of capsular polysaccharides from the seven serotypes of Streptococcus pneumoniae most commonly isolated from children 6 years of age or younger, coupled to a nontoxic variant of diphtheria toxin; used as an active immunizing agent for infants and children at risk for pneumococcal disease, administered intramuscularly.pneumococcal vaccine polyvalent a preparation of purified capsular polysaccharides from the 23 serotypes of Streptococcus pneumoniae causing the majority of pneumococcal disease; used as an active immunizing agent in persons over 2 years of age, administered intramuscularly.poliovirus vaccine inactivated (IPV) a preparation of killed polioviruses of three types, given in a series of intramuscular or subcutaneous injections to immunize against poliomyelitis. It does not induce intestinal immunity and so is not effective for poliovirus eradication in areas where wild-type polioviruses still exist in large numbers. However, it does not cause vaccine-associated paralytic poliomyelitis and so is preferred for routine immunization in areas where the risk of infection by a wild-type poliovirus is very low, as in the United States. Called also Salk vaccine.poliovirus vaccine live oral (OPV) an oral vaccine against poliomyelitis consisting of three types of live, attenuated polioviruses. It is given orally, often on a sugar cube, and so is convenient for administration to children and large groups of people. It induces both humoral and intestinal immunity, so is useful for immunization and poliomyelitis eradication in areas where wild-type polioviruses have not been eradicated. However, it can cause vaccine-associated paralytic poliomyelitis in persons newly vaccinated with it and their contacts, which is considered an unjustifiable risk in countries such as the United States, where the risk of exposure to wild-type polioviruses is very low. Thus, for routine immunization in the United States, it has been superseded by vaccine inactivated" >poliovirus vaccine inactivated. Called also Sabin vaccine.polyvalent vaccine a vaccine prepared from cultures or antigens of more than one strain or species.purified chick embryo cell vaccine an inactivated virus vaccine used for pre- and postexposure rabies immunization, prepared from rabies virus grown in cultures of chicken fibroblasts; administered intramuscularly.rabies vaccine any of various vaccines against rabies consisting of inactivated virus, used for preexposure immunization to persons at high risk of exposure, such as veterinarians, and for postexposure prophylaxis in conjunction with globulin" >rabies immune globulin. See human diploid cell v., purified chick embryo cell v., and rabies v. adsorbed.rabies vaccine adsorbed (RVA) a rabies vaccine prepared from rabies virus grown in cultures of fetal rhesus monkey lung and inactivated; administered intramuscularly.rotavirus vaccine live oral a live virus vaccine produced from a mixture of four types of rotavirus, used to immunize infants against rotaviral gastroenteritis.rubella and mumps virus vaccine live a combination of live attenuated rubella and mumps viruses, administered subcutaneously for simultaneous immunization against rubella and mumps.rubella virus vaccine live a live attenuated virus vaccine used for immunization against rubella, usually administered as the combination vaccine" >measles, mumps, and rubella virus vaccine.Sabin vaccine poliovirus vaccine live oral.Salk vaccine poliovirus vaccine inactivated.subunit vaccine a vaccine produced from specific protein subunits of a virus and thus having less risk of adverse reactions than whole virus vaccines.typhoid vaccine any of several preparations of Salmonella typhi used for immunization against typhoid fever, including a parenteral heat- and phenol-inactivated bacteria vaccine, an oral live vaccine prepared from the attenuated strain Ty21a, and a parenteral vaccine prepared from typhoid Vi capsular polysaccharide.varicella virus vaccine live a preparation of live, attenuated human herpesvirus 3 (varicella-zoster virus) administered subcutaneously for production of immunity to varicella and herpes zoster.yellow fever vaccine a preparation of attenuated yellow fever virus, used to immunize against yellow fever.

vac·cine

(vak'sēn, vak-sēn'), Although this word is correctly stressed on the first syllable, in U.S. usage it is often stressed on the second syllable.Originally, the live vaccine (vaccinia, cowpox) virus inoculated in the skin as prophylaxis against smallpox and obtained from the skin of calves inoculated with seed virus. Usage has extended the meaning to include essentially any preparation intended for active immunologic prophylaxis; for example, preparations of killed microbes of virulent strains or living microbes of attenuated (variant or mutant) strains; or microbial, fungal, plant, protozoal, or metazoan derivatives or products. Method of administration varies according to the vaccine, inoculation being the most common, but ingestion is preferred in some instances and nasal spray is used occasionally. Synonym(s): vaccinum [L. vaccinus, relating to a cow]

vaccine

(văk-sēn′, văk′sēn′)n.a. A preparation of a weakened or killed pathogen, such as a bacterium or virus, or of a portion of the pathogen's structure that upon administration to an individual stimulates antibody production or cellular immunity against the pathogen but is incapable of causing severe infection.b. A preparation from the cowpox virus that protects against smallpox when administered to an individual.

vaccine

Immunology A mixture of live, live-attenuated, killed, complete or incomplete microorganisms or their products, that contains antigens capable of stimulating production of specific protective antibodies against a pathogen; vaccines may be biochemically synthesized or made by recombinant DNA techniques Effective vaccines Diphtheria, HAV, HBV, influenza, measles, pertussis, S pneumoniae, tetanus

vac·cine

(vak-sēn') Any preparation intended for active immunologic prophylaxis, e.g., preparations of killed microbes of virulent strains or living microbes of attenuated (variant or mutant) strains, or microbial, fungal, plant, protozoal, or metazoan derivatives or product. [L. vaccinus, relating to a cow, vacca]

vaccine

A suspension of microorganisms of one particular type that have been killed or modified so as to be safe, given to promote the production of specific ANTIBODIES to the organism for purposes of future protection against infection.

vaccine

a preparation containing live, attenuated (see ATTENUATION).or inactivated (killed) microorganisms (or some part or product of them), that is used to stimulate an IMMUNE RESPONSE in the recipient, which gains IMMUNITY. The Salk polio vaccine is an example of a vaccine that contains inactivated viruses, whereas the Sabin polio vaccine is a LIVE VACCINE. The name comes from the Latin vaccinus, ‘of cows’, and relates to the work of Edward JENNER on cowpox. Vaccines are not quick-acting, but rely on the recipient to build up a supply of ANTIBODIES gradually. Compare SERUM (3). See also COMBINATION VACCINE, DNA VACCINE, SUBUNIT VACCINE.

Vaccine

A preparation using a non-infectious element or relative of a particular virus or bacteria, and administered with the intention of halting the progress of an infection, or completely preventing it.Mentioned in: Encephalitis, Hepatitis A, Hepatitis B, Hepatitis E, Smallpox

vac·cine

(vak-sēn') Originally, live vaccine (vaccinia, cowpox) virus inoculated in skin as prophylaxis against smallpox and obtained from skin of calves inoculated with seed virus. Usage has extended the meaning to include essentially any preparation intended for active immunologic prophylaxis. [L. vaccinus, relating to a cow, vacca]

Patient discussion about vaccine

Q. Do Vaccines cause Autism? I have heard all over the news lately that the vaccines we give our children can cause Autism. Is this true? Is it dangerous? Should I vaccinate my one year old son?A. NO
Andrew Wakefield MD started the controversy when publish the idea in Lancet. He was paid 130,000 dollars to lie
Check this link for full story:
http://www.thedoctorsvideos.com/video/749/MMR-and-Autism-The-Andrew-Wakefield-Story

Q. Who Should Receive the Flu Vaccine? Should I go get vaccinated for the flu? I have been told it is advised only for certain people, so who should receive this vaccine?A. before you would like to go on with any vaccination, you should check out this very long list of links and create your own opinion:
http://www.aegis.ch/neu/links.html
at the bottom you will also find links in english. vaccinations in general are very disputable/dubious and it is probably time that we learn about it.

Q. Does the flu vaccine protect from all kinds of flu? If I get a flu vaccine does that mean I am completely protected from getting the flu?A. No, the vaccine does not give complete protection from all the flu types out there. The vaccine protects from the most common types of flu, which are: H3N2, H1N1 and one B virus.

More discussions about vaccine
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vaccine


Related to vaccine: HPV vaccine, Polio vaccine
  • noun

Synonyms for vaccine

noun inoculation

Synonyms

  • inoculation
  • injection
  • immunization

Synonyms for vaccine

noun immunogen consisting of a suspension of weakened or dead pathogenic cells injected in order to stimulate the production of antibodies

Synonyms

  • vaccinum

Related Words

  • DPT vaccine
  • immunizing agent
  • immunogen
  • pneumococcal vaccine
  • Pneumovax
  • poliovirus vaccine
  • proteosome
  • proteosome vaccine
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