释义 |
uroporphyrinogen
uroporphyrinogen [u″ro-por″fĭ-rin´o-jen] a porphyrinogen formed from porphobilinogen; it is a precursor of uroporphyrin and coproporphyrinogen.por·phy·rin·o·gens (pōr'fi-rin'ō-jenz), Intermediates in the biosynthesis of heme, as follows: four porphobilinogens condense to form uroporphyrinogens I and III (giving rise to side products uroporphyrins I and III) that are decarboxylated to form coproporphyrinogens I and III (giving rise to side products coproporphyrins I and III); coproporphyrinogen III is oxidized to protoporphyrinogen III (IX), which is then oxidized to form protoporphyrin III (IX) (this last intermediate adds ferrous iron to yield heme); certain porphyrinogens are elevated in certain porphyrias.por·phy·rin·o·gens (pōr'fir-in'ō-jenz) Intermediates in the biosynthesis of heme; certain porphyrinogens are elevated in certain porphyrias. |