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DictionarySeecarcinomaurothelial carcinoma Note: This page may contain terms or definitions that are offensive or inappropriate for some readers.urothelial carcinomaa malignant neoplasm derived from transitional epithelium, occurring chiefly in the urinary bladder, ureters, or renal pelves (especially if well differentiated); frequently papillary; these carcinomas are graded according to the degree of anaplasia. So-called transitional cell carcinoma of the upper respiratory tract is more properly classified as squamous cell carcinoma. Transitional cell carcinoma is also a rare tumor of the ovary. Synonym(s): transitional cell carcinomaur·o·the·li·al car·ci·no·ma (yūr'ō-thē'lē-ăl kahr'si-nō'mă) A malignant neoplasm derived from transitional epithelium, occurring chiefly in the urinary bladder, ureters, or renal pelves (especially if well differentiated); frequently papillary; these carcinomas are graded according to the degree of anaplasia. So-called transitional cell carcinoma of the upper respiratory tract is more properly classified as squamous cell carcinoma. Transitional cell carcinoma is also a rare tumor of the ovary. carcinoma (kar?sin-o'ma ) [ carcin- + -oma] A malignant tumor that occurs in epithelial tissue and may infiltrate local tissues or produce metastases. It may affect almost any organ or part of the body and spread by direct extension, through lymphatics, or through the bloodstream. The causes vary with tumor type. Patient careOptimal patient care includes: identifying and explaining to patient and family the type of cancer and its typical natural history; options for treatment, side effects of treatments, expected response of the cancer to the treatment, best predictions for recovery and life expectancy, availability of clinical trials, alternative and complementary therapies, and the potential benefit of referral to specialty cancer centers. acinar cell carcinoma of the pancreasA rare carcinoma that arises from pancreatic cells that manufacture digestive proteins, such as lipase, chymotrypsin, or alpha-1-antitrypsin.alveolar cell carcinomaA type of lung carcinoma.BASAL CELL CARCINOMABASAL CELL CARCINOMAbasal cell carcinoma Abbreviation: BCC The most common human cancer, typically found on skin exposed to sun or other forms of ultraviolet light. Although it is sometimes locally invasive, it rarely metastasizes to other organs. Typically it begins as a small, shiny papule. The lesion enlarges to form a whitish border around a central depression or ulcer that may bleed. When the lesion reaches this stage, it is often called a rodent ulcer. After biopsy, the removal method used is determined by the size, location, and appearance of the lesion. Synonym: basal cell epithelioma; epithelial cancer See: illustrationillustrationbronchioloalveolar carcinomaA relatively rare form of non-small cell lung cancer consisting of columnar cells, and in which the tumor arises in the periphery of the lung within the septal borders of the alveoli, which the tumor tends to preserve. The tumor cells frequently produce mucin. bronchogenic carcinomaLung cancer.chorionic carcinomaChoriocarcinoma.choroid plexus carcinomaA cancer that arises from the cells that line the fluid-filled cavities (ventricles) of the brain.carcinoma of the colon See: colorectal cancercolorectal carcinomaColorectal cancer.carcinoma cuniculatumAny slowly growing squamous cell carcinoma of the skin, typically presenting as a gradually enlarging warty tumor. ductal carcinoma in situ of breast See: ductal carcinoma in situ of breastembryonal carcinomaAn aggressive germ cell tumor that may metastasize widely. It can occur in young adults of either sex. epidermoid carcinomaSquamous cell carcinoma.carcinoma erysipelatoidesMetastatic spreading of cancer, usually from an internal organ to the skin, to which the spreading tumor gives a red, inflammatory appearance.giant cell carcinomaCarcinoma marked by the presence of unusually large cells.glandular carcinomaAdenocarcinoma.keratinocyte carcinomaA cancer arising from cells in the epidermis. It includes basal cell carcinomas, keratoacanthomas, and squamous cell carcinomas of the skin. Most keratinocyte carcinomas arise in sun-exposed areas of the body, such as the ears, the temples, the forehead or the nose. carcinoma in situ Abbreviation: CIS Malignant cell changes in the epithelial tissue that do not extend beyond the basement membrane.medullary carcinomaCarcinoma in which there is a predominance of cells and little fibrous tissue.melanotic carcinomaCarcinoma containing melanin.mucinous carcinomaCarcinoma in which the glandular tissue secretes mucin.neuroendocrine carcinomaAny of a diverse group of malignancies, such as carcinoid, islet cell tumors, neuroblastoma, and small-cell carcinomas of the lung. All have dense core granules and produce polypeptides that can be identified by immunochemical methods. oat cell carcinomaA poorly differentiated carcinoma of the bronchus that contains small oat-shaped cells. Synonym: small cell carcinomacarcinoma of pancreasPancreatic cancer.pancreatic carcinomaPancreatic cancer.papillary carcinoma of the thyroid See: papillary carcinoma of the thyroidrenal cell carcinomaA carcinoma that arises from the proximal tubular cells of the kidney. In 2008 the American Cancer Society estimated there would be about 56,700 new patients diagnosed with renal cell carcinoma and about 13,700 deaths from it. Synonym: hypernephroma; kidney cancerSymptomsBecause of its location in the retroperitoneum, renal cell carcinoma may grow to a relatively large size before it manifests obvious symptoms. The most common findings are blood in the urine (hematuria), flank pain, or a flank mass. Some patients develop fevers, weight loss, or symptoms caused by hormones excreted by the tumor. These hormones (parathyroid-like hormone or erythropoietin) occasionally cause hypercalcemia or abnormal increases in the red blood cell count (erythrocytosis). TreatmentSurgical removal of the affected kidney may be curative for those patients whose tumor has not spread outside the perirenal fascia. Treatment options are less successful for patients with metastatic disease because renal cell carcinomas are relatively resistant to chemotherapy. sarcomatoid carcinomaA carcinoma that contains both epithelial and mesenchymal components. This cancer may arise from cells in the kidney, urinary bladder, or lung. scirrhous carcinomaHard cancer.small cell carcinomaOat cell carcinoma.SQUAMOUS CELL CARCINOMAsquamous cell carcinomaCarcinoma that develops primarily from squamous cells, e.g., of the skin or in the mouth, lungs, bronchi, esophagus, or cervix. Synonym: epidermoid carcinoma See: illustrationillustrationillustrationthymic carcinomaA carcinoma found in the anterior mediastinum, usually a squamous cell carcinoma, spindle cell carcinoma, or lymphoepithelioma. Many of these tumors release chemically active substances that cause paraneoplastic syndromes. transitional cell carcinomaA carcinoma that originates in cells that line the urinary tract, e.g., in cells that line the inner kidney, the ureters, or the urinary bladder. Synonym: urothelial carcinomaurothelial carcinomaTransitional cell carcinoma.AcronymsSeeUC |