Steele-Richardson-Olszewski syndrome


Steele-Richardson-Olszewski syndrome

 [stēl-rich´erd-sun-ol-shev´ske] a progressive neurological disorder, having an onset during the sixth decade, characterized by supranuclear ophthalmoplegia, especially paralysis of the downward gaze, pseudobulbar palsy, dysarthria, dystonic rigidity of the neck and trunk, and dementia.

pro·gress·ive su·pra·nu·cle·ar pal·sy

[MIM*601104] a slowly progressive, ultimately fatal neurologic disorder with onset after the age of 40 years. Initial symptoms include difficulties in balance with repeated falls, ocular motility disturbances, slurred speech, and dysphasia; later findings include axial dystonia, supranuclear ophthalmoplegia, pseudobulbar palsy, and parkinsonism (but without tremor and with a poor response to l-dopa). Synonym(s): Steele-Richardson-Olszewski disease, Steele-Richardson-Olszewski syndrome

Steele-Richardson-Olszewski syndrome

See PROGRESSIVE SUPRANUCLEAR PALSY.

Olszewski,

Jerzy, Polish-Canadian neuropathologist, 1913-1966. Steele-Richardson-Olszewski disease - Synonym(s): Steele-Richardson-Olszewski syndromeSteele-Richardson-Olszewski syndrome - see under Steele

Richardson,

John Clifford, Canadian neurologist, 1909–. Richardson rodSteele-Richardson-Olszewski disease - Synonym(s): Steele-Richardson-Olszewski syndromeSteele-Richardson-Olszewski syndrome - see under Steele

Steele,

John C., Canadian neurologist, d. 1968. Steele-Richardson-Olszewski disease - Synonym(s): Steele-Richardson-Olszewski syndromeSteele-Richardson-Olszewski syndrome - a progressive neurologic disorder characterized by a supranuclear paralysis of vertical gaze, retraction of eyelids, exophoria under cover, dysarthria, and dementia. Synonym(s): progressive supranuclear palsy; Steele-Richardson-Olszewski disease