provirus

pro·vi·rus

P0623050 (prō′vī′rəs, prō-vī′-)n. pl. pro·vi·rus·es A form of a virus that allows it to be integrated into the genome of a host cell and to replicate in concert with the cell's genetic material without causing cell lysis.

pro′vi′ral (-rəl) adj.

provirus

(ˈprəʊˌvaɪrəs) n (Pathology) the inactive form of a virus in a host cell

pro•vi•rus

(ˈproʊˌvaɪ rəs, proʊˈvaɪ-)

n., pl. -rus•es. a viral form that is incorporated into the genetic material of a host cell. [1945–50]

Thesaurus

Noun

provirus - cDNA copy of the RNA genome of a retrovirus; the genetic material of a virus as incorporated into and able to replicate with the genome of a host cellcDNA, complementary DNA - single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase

Translations

Provirus

provirus

[prō′vī·rəs] (virology) The phage genome.

Provirus

the genome or part of the genome of a virus integrated with the genetic material of the host cell into united molecules of deoxyribonucleic acid (DNA). A provirus may result from the infection of cells by certain temperate viruses. Both DNA-containing and some RNA-containing viruses, such as oncornaviruses, can become proviruses. In the latter case, the formation of a provirus is preceded by reverse transcription, that is, by DNA synthesis using the viral RNA molecule as a template.

The provirus replicates during the division of cell chromosomes, with which it may be transmitted from cell to cell. Some of the provirus genes, and occasionally most of them, are usually inactive (repressed) and do not form corresponding proteins. Active provirus genes may cause hereditary changes in cell properties. Examples of such changes are lysogenic conversion and transformation of cells caused by oncogenic viruses. Under certain conditions, the provirus becomes independent of the regulatory systems and begins replicating autonomously. In the case of DNA-containing viruses, this process is accompanied by the liberation of viral genetic material from the cell chromosome. The mechanisms of the formation, functioning, and replication (induction) of the provirus have been studied most thoroughly in temperate bacteriophages. In such viruses, the provirus is called a prophage.

V. I. AGOL

provirus

[pro-vi´rus] a DNA transcript of an virus" >RNA virus that migrates from the cytoplasm into the nucleus and integrates into the host genome by crossing over so that it will be thus replicated in the daughter cells.

pro·vi·rus

(prō-vī'rŭs), The precursor of an animal virus, usually a retrovirus; theoretically analogous to the prophage in bacteria, the provirus is integrated in the nucleus of infected cells and can be activated in response to certain stimuli.

provirus

(prō′vī′rəs, prō-vī′-)n. pl. provi·ruses A form of a virus that allows it to be integrated into the genome of a host cell and to replicate in concert with the cell's genetic material without causing cell lysis.

pro′vi′ral (-rəl) adj.

pro·vi·rus

(prō-vī'rŭs) The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus

the DNA of a VIRUS that has integrated into the DNA of the host CELL and is transmitted from one cell generation to the next in this state. No infective virus particles are produced. The provirus can excise from the host's DNA and resume a productive viral cycle with the production of virus particles.

pro·vi·rus

(prō-vī'rŭs) The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

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Words related to provirus

noun cDNA copy of the RNA genome of a retrovirus

Related Words