单词 | sotalol |
释义 | sotalolso·ta·lolS5626350 (sō′tə-lôl′, -lōl′)sotalolsotalol[so´tah-lol]sotalol(sō′tə-lôl′, -lōl′)Betapace AFA racemic mixture of d- and l-sotalol, with beta-blocking (class II) and cardiac action potential duration prolongation (class-III antiarrhythmic properties).Adverse effects Fatigue, bradycardia, proarrhythmia, dyspnea, diarrhoea, nausea, vomiting, QT-interval prolongation, nonspecific increase in liver enzymes. sotalolBetapace®, Sotacor® Cardiology A class II beta blocker that ↑ myocardial action potential duration, ↑ cardiac refractory period, lengthens QT interval; sotalol is used for conduction block, A Fib, torsade de pointes, angina, HTN, suppress PVCs, ventricular tachyarrhythmias Adverse effects Proarrhythmia due to ↑ β blockade; it may aggravate pre-existing arrhythmias–eg, sinus bradycardia, provoke new arrhythmias–eg, torsade de points–±2.5%, exacerbate CHF, hypotension, bronchospasm, fatigue, dizziness, dyspnea, headache. See β-blocker, SWORD.sotalolA long-acting beta-blocker drug used to treat irregularity of the heart action. Brand names are Beta-Cardone and Sotacor. |
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