physiologic jaundice of newborn

physiologic jaundice of newborn

Neonatal jaundice Neonatology Yellowing of skin during the newborn period, caused by ↑ BR level in the blood, due to immaturity of liver function plus destruction of RBCs; seen between days 2 and 5, clears by 2 wks Risk factors, jaundice Prematurity DiffDx Nonphysiologic, prolonged, or pathologic jaundice in newborn, biliary atresia, ABO and/or Rh incompatibility, galactosemia, cephalhematoma, polycythemia, G6PD deficiency, neonatal sepsis, congenital infection–CMV, toxoplasmosis, syphilis, herpes, rubella, late pregnancy use of sulfa drugs by mother, Crigler-Najjar syndrome, spherocytosis, cystic fibrosis, breast-milk jaundice, pyruvate kinase deficiency, thalassemia, Gilbert's syndrome, congenital hypothyroidism, Lucey-Driscol syndrome, Gaucher's disease, Niemann-Pick disease.