azole

az·ole

A0561500 (ăz′ōl′, ā′zōl′)n. Any of a class of organic compounds that have a five-membered heterocyclic ring with at least one nitrogen and two double bonds and that also may contain another heteroatom.

azole

(ˈeɪzəʊl; əˈzəʊl) n1. (Elements & Compounds) an organic five-membered ring compound containing one or more atoms in the ring, the number usually being specified by a prefix: diazole; triazole. 2. (Elements & Compounds) a less common name for pyrrole[from azo- + -ole¹, on the model of diazole]

az•ole

(ˈæz oʊl, əˈzoʊl)

n. any of a group of five-membered heterocyclic compounds containing one or more nitrogen atoms in the ring. [1895–1900; see azo, -ole²]

Translations

azole

pyr·role

(pir'ōl), Divinylenimine; a heterocyclic compound found in many biologically important substances, for example, heme. Synonym(s): azole, imidole

azole

(ăz′ōl′, ā′zōl′)n. Any of a class of organic compounds that have a five-membered heterocyclic ring with at least one nitrogen and two double bonds and that also may contain another heteroatom.

azole

Any of a family of broad-spectrum antifungals, including ketoconazole, fluconazole and itraconazole.

Indications
Blastomyocosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, paracoccidoidomycosis and in sporotrichosis.

Adverse effects
Nausea, vomiting, anorexia, rash, pruritus, nonspecific increased liver enzymes, anaemia, leukopenia, thrombocytopenia, headache and others.

Drug interactions
Plasma levels of azoles are decreased by antacids, H2-receptor antagonists, sucralfate, isoniazid, phenytoin and rifampin.

azole

Infectious disease One of a family of synthetic broad-spectrum antifungal antibiotics–including ketoconazole, fluconazole, itraconazole Indications Various azoles have established efficacy in treating blastomyocosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, paracoccidoidomycosis and sporotrichosis Adverse effects N&V, anorexia, rash, pruritus, nonspecific ↑ liver enzymes, anemia, leukopenia, thrombocytopenia, headache, etc Drug interactions Plasma levels of azoles are ↓ by antacids, H₂-receptor antagonists, sucralfate, isoniazid, phenytoin, rifampin. See Fluconazole, Itraconazole, Ketoconazole.

pyr·role

(pir'ōl) A heterocyclic compound found in many biologically important substances.
Synonym(s): azole, imidole.

单词	azole
释义	azole az·ole A0561500 (ăz′ōl′, ā′zōl′)n. Any of a class of organic compounds that have a five-membered heterocyclic ring with at least one nitrogen and two double bonds and that also may contain another heteroatom. azole (ˈeɪzəʊl; əˈzəʊl) n1. (Elements & Compounds) an organic five-membered ring compound containing one or more atoms in the ring, the number usually being specified by a prefix: diazole; triazole. 2. (Elements & Compounds) a less common name for pyrrole[from azo- + -ole¹, on the model of diazole] az•ole (ˈæz oʊl, əˈzoʊl) n. any of a group of five-membered heterocyclic compounds containing one or more nitrogen atoms in the ring. [1895–1900; see azo, -ole²] Translations azole azole [′ā‚zōl] (organic chemistry) One of a class of organic compounds with a five-membered N-heterocycle containing two double bonds; an example is 1,2,4-triazole. azole pyr·role (pir'ōl), Divinylenimine; a heterocyclic compound found in many biologically important substances, for example, heme. Synonym(s): azole, imidole azole (ăz′ōl′, ā′zōl′)n. Any of a class of organic compounds that have a five-membered heterocyclic ring with at least one nitrogen and two double bonds and that also may contain another heteroatom. azole Any of a family of broad-spectrum antifungals, including ketoconazole, fluconazole and itraconazole. Indications Blastomyocosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, paracoccidoidomycosis and in sporotrichosis. Adverse effects Nausea, vomiting, anorexia, rash, pruritus, nonspecific increased liver enzymes, anaemia, leukopenia, thrombocytopenia, headache and others. Drug interactions Plasma levels of azoles are decreased by antacids, H2-receptor antagonists, sucralfate, isoniazid, phenytoin and rifampin. azole Infectious disease One of a family of synthetic broad-spectrum antifungal antibiotics–including ketoconazole, fluconazole, itraconazole Indications Various azoles have established efficacy in treating blastomyocosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, paracoccidoidomycosis and sporotrichosis Adverse effects N&V, anorexia, rash, pruritus, nonspecific ↑ liver enzymes, anemia, leukopenia, thrombocytopenia, headache, etc Drug interactions Plasma levels of azoles are ↓ by antacids, H₂-receptor antagonists, sucralfate, isoniazid, phenytoin, rifampin. See Fluconazole, Itraconazole, Ketoconazole. pyr·role (pir'ōl) A heterocyclic compound found in many biologically important substances. Synonym(s): azole, imidole.
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