VCAM-1

Vascular cell adhesion molecule 1. A cell-surface sialoglycoprotein encoded by VCAM1 on 1p32-p31, which belongs to the Ig superfamily, is expressed by cytokine-activated endothelium, and is involved in early inflammation. It mediates leukocyte-endothelial cell adhesion and signals transduction, recruiting monocytes and lymphocytes to the endothelial cell surface, triggering a chronic inflammatory response linked to atherosclerosis and rheumatoid arthritis.

vascular cell adhesion molecule-1

VCAM-1

A cell adhesion molecule that helps bind white blood cells such as lymphocytes or monocytes to the endothelium of blood vessels. Synonym: vascular cell adhesion protein