transferase

trans·fer·ase

T0316400 (trăns′fə-rās′, -rāz′)n. Any of a class of enzymes that catalyze the transfer of a chemical group, such as a phosphate or amine, from one molecule to another.

transferase

(ˈtrænsfəˌreɪs) n (Biochemistry) any enzyme that catalyses the transfer of a chemical group from one substance to another

trans•fer•ase

(ˈtræns fəˌreɪs, -ˌreɪz)

n. any of a group of enzymes, as the transaminases, that effect the transfer of an organic group from one compound to another. [1945–50]

Thesaurus

Noun

transferase - any of various enzymes that move a chemical group from one compound to another compoundenzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactionsribonuclease, ribonucleinase, RNase - a transferase that catalyzes the hydrolysis of ribonucleic acidaminopherase, aminotransferase, transaminase - a class of transferases that catalyze transamination (that transfer an amino group from an amino acid to another compound)

Translations

Transferase

transferase

[′tranz·fə‚rās] (biochemistry) Any of various enzymes that catalyze the transfer of a chemical group from one molecule to another.

Transferase

any of a class of enzymes that catalyze the transfer of a chemical group from one compound (the donor) to another (the acceptor). Transferases are common in plant and animal tissues, as well as in microorganisms. They play a leading role in intermediary metabolism, participating in the transformations of carbohydrates, amino acids, nucleic acids, lipids, and other biologically important compounds.

The transferase class includes more than 450 enzymes, divided by the chemical nature of the group being transferred into subclasses. Examples include the subclasses that catalyze the transfer of single-carbon groups (methyltransferases), glycosyl groups (glycosyltransferases), nitrogen-bearing groups (aminotransferases, or transaminases), and phosphate groups (phosphotransferases). The transferases of the various subclasses have different coenzymes.

The mechanism of the catalytic action of the transferases studied to date includes the formation of an intermediate made up of the enzyme and group being transferred. For example, in the transfer of the acetyl radical (CH₃CO—), an acetylated enzyme is formed in the first stage of the reaction, followed by the transfer of the radical to the acceptor and the liberation of the enzyme. The names of transferases are formed according to the sequence dononacceptor-transferred group-transferase. For example, the enzyme that catalyzes the transfer of the phosphate group from adenosinetriphosphate (ATP) to creatine is called ATP:creatine-phosphotransferase. Several transferases have been obtained in crystalline form.

REFERENCES

Nomenklatura fermentov. Moscow, 1966. (Translated from English.)
Kretovich, V. L. Vvedenie v enzimologiiu, 2nd ed. Moscow, 1974.

V. V. ZUEVSKII

transferase

[trans´fer-ās] an enzyme that catalyzes the transfer, from one molecule to another, of a chemical group that does not exist in free state during the transfer.

transferase

(trăns′fə-rās′, -rāz′)n. Any of various enzymes that catalyze the transfer of a chemical group, such as a phosphate or amine, from one molecule to another.

transferase

Any enzyme that catalyses the movement of atoms or groups of atoms from one molecule to another. A kinase adds a phosphate group to a substrate such as an amino acid.

transferase

any enzyme that catalyses the transfer of a chemical group such as amino, methyl or alkyl from one SUBSTRATE to another substrate.

transferase

Related to transferase: Glucuronyl transferase, Alanine transferase, Peptidyl transferase, Terminal transferase

noun

Words related to transferase

noun any of various enzymes that move a chemical group from one compound to another compound

Related Words

enzyme
ribonuclease
ribonucleinase
RNase
aminopherase
aminotransferase
transaminase