pulmonary renal syndrome

pulmonary renal syndrome

Nephrology An idiopathic condition characterized by pulmonary hemorrhage, immune crescent glomerulonephritis, and antineutrophil cytoplasmic antibodies; pulmonary-renal 'syndrome' may be defined as a heterogeneous group of multisystem diseases–eg, Goodpasture syndrome, Wegener's granulomatosus, collagen vascular disease–in particular SLE, polyarteritis nodosa, Henoch-Schönlein purpura, and various other conditions, which have prominent pulmonary and renal components and microangiopathic vasculitis Clinical Asymptomatic pulmonary infiltrates or pulmonary hemorrhage with episodic cough, hemoptysis, dyspnea and widespread alveolar infiltrates on CXR; renal involvement is characterized by microscopic hematuria, RBC casts, ↑ creatinine