| 释义 |
DictionarySeeTRALIEncyclopediaSeeinjurytransfusion-related acute lung injury
transfusion-related acute lung injuryadult respiratory distress syndrome (ARDS) occurring within 4 hours of transfusion. The estimated frequency is 1 in 5000 transfusions and the mechanism remains poorly understood. The prognosis is much better than with most other cases of ARDS.
See also: adult respiratory distress syndrome. transfusion-related acute lung injury Transfusion medicine 1. A type of ARDS characterized by acute noncardiogenic pulmonary edema–pulmonary white-out–and hypoxia within 4 hrs of transfusing a blood product from a multiparous donor containing plasma with potent antigranulocytic antibodies. See Adult respiratory distress syndrome.2. A nonimmune response to transfusion of packed RBCs, attributed to platelet-specific antibodies Clinical Severe thrombocytopenia–eg, < 10 x 109/L–5–10 days after packed RBCs in Pt sensitized by prior transfusion or pregnancy Management Steroids, IVIG Prognosis Spontaneous recovery. See Transfusion.trans·fu·sion-re·lated a·cute lung in·ju·ry (trans-fyūzhŭn-rē-lātĕd ă-kyūt lŭng injŭr-ē) Adult respiratory distress syndrome (ARDS) occurring within 4 hours of transfusion; mechanism remains poorly understood. The prognosis is much better than with most other cases of ARDS. LegalSeeInjury |