American mandrake


A perennial herb once used as an anthelmintic, emetic, purgative, and liver tonic; its marked purgative activity precludes its therapeutic use; a semisynthetic derivative, etoposide, is used to treat cancers
Toxicity Dermatitis, diarrhea, nausea, vomiting, severe gastroenteritis, and possibly death; mayapple is regarded by the FDA as ‘unsafe’