transient aplastic crisis


transient aplastic crisis (TAC),

temporary suppression of erythropoiesis, due usually to viral infection (e.g., Parvovirus B-19); may be particularly severe in people with hemolytic anemias (e.g., sickle cell disease, thalassemia, hereditary spherocytosis).

transient aplastic crisis

Abbreviation: TAC
A serious complication of infection with human parvovirus B-19 infection in patients with chronic hemolytic anemia such as sickle cell disease. This virus causes erythema infectiosum. See: erythema infectiosumSee also: crisis