Shwartzman reaction


Shwartz·man phe·nom·e·non

(shwarts'măn), that a rabbit injected intradermally with a small quantity of lipopolysaccharide (endotoxin) followed by a second intravenous injection 24 hours later will develop a hemorrhagic and necrotic lesion at the site of the first injection.
See also: generalized Shwartzman phenomenon. Synonym(s): Shwartzman reaction

Shwartzman,

Gregory, Russian bacteriologist in U.S., 1896-1965. generalized Shwartzman phenomenon - death occurs in an animal that has been injected with a primary injection of endotoxin-containing filtrate and secondary injection given intravenously 24 hours apart. Synonym(s): Sanarelli phenomenon; Sanarelli-Shwartzman phenomenonSanarelli-Shwartzman phenomenon - Synonym(s): generalized Shwartzman phenomenonShwartzman phenomenon - a rabbit injected intradermally with a small quantity of endotoxin followed by a second intravenous injection 24 hours later will develop a hemorrhagic and necrotic lesion at the site of the first injection. Synonym(s): Shwartzman reactionShwartzman reaction - Synonym(s): Shwartzman phenomenon