| 释义 |
tuberculin
tu·ber·cu·lin T0400300 (to͝o-bûr′kyə-lĭn, tyo͝o-)n. A sterile liquid containing proteins extracted from cultures of tubercle bacilli and used in tests for tuberculosis.
[Latin tūberculum, tubercle; see tubercle + -in.]tuberculin (tjʊˈbɜːkjʊlɪn) n (Medicine) a sterile liquid prepared from cultures of attenuated tubercle bacillus and used in the diagnosis of tuberculosistu•ber•cu•lin (tʊˈbɜr kyə lɪn, tyʊ-)
n. a sterile liquid prepared from cultures of the tubercle bacillus, used in a scratch test for tuberculosis. Thesaurus| Noun | 1. | tuberculin - a sterile liquid containing a purified protein derivative of the tuberculosis bacterium; used in the diagnosis of tuberculosisliquid - fluid matter having no fixed shape but a fixed volume |
Translationstuberculin
tuberculin a sterile liquid prepared from cultures of attenuated tubercle bacillus and used in the diagnosis of tuberculosis Tuberculin a diagnostic agent used to detect an allergic reaction in individuals infected with tubercle bacilli. It was first discovered by R. Koch. Several types of tuberculin are produced in the USSR, as follows. Liquid tuberculin, or old tuberculin (OT), is prepared by boiling a bouillon culture of tubercle bacilli. Purified protein derivative of tuberculin (PPD) is prepared by adding to a filtrate of bacilli various chemical substances that precipitate proteins, and then purifying the mixture. Liquid purified protein derivative of tuberculin (PPD-L) is prepared by making standard dilutions of purified protein derivative of tuberculin. The tuberculin test detects the presence of tuberculosis; those persons who react positively should then be vaccinated against the disease. The tuberculin test serves as a means of both early diagnosis and of evaluation of the course of tuberculosis. Only the intracutaneous Mantoux test is in wide use in the USSR. Veterinaries use the tuberculin test to diagnose tuberculosis in animals. The tuberculin is occasionally injected subcutaneously; more commonly, it is injected intracutaneously or into the conjunctival sac. Animals that react positively are considered tuberculotic. A positive reaction is manifested by inflammatory edema after an intracutaneous injection and by purulent conjunctivitis in the eye test. tuberculin[tə′bər·kyə·lən] (immunology) A preparation containing tuberculoproteins derived from Mycobacterium tuberculosis used in the tuberculin test to determine sensitization to tubercle bacilli. tuberculin
tuberculin [too-ber´ku-lin] a sterile liquid containing the growth products of, or specific substances extracted from, the tubercle bacillus; used in various forms in the diagnosis of tuberculosis (see tuberculin test).Old tuberculin a sterile solution of a heat-concentrated filtrate of tubercle bacillus culture grown on a special medium, used for tuberculin tests.PPD tuberculin (purified protein derivative tuberculin) a sterile solution of a purified protein fraction precipitated from a filtrate of tubercle bacillus culture grown on a special medium, used for tuberculin tests.tuberculin test any of a large number of skin tests for tuberculosis using a variety of different types of tuberculin and methods of application. The most reliable procedure, now standard, is intradermal injection (the mantoux test) of PPD (purified protein derivative); a positive result consists of a palpable and visible area of erythema and induration greater than 10 mm in diameter developing around the site of injection 48 to 72 hours after the injection. Intermediate strength tuberculin (5 TU) is generally used to test adults; a positive result is virtually diagnostic of a previous or current infection with Mycobacterium tuberculosis. Persons with a negative test are retested with second strength tuberculin (250 TU); in this test a positive reaction is frequently due to atypical mycobacteria infection and is thus nonspecific; a negative result indicates either absence of tuberculosis or the presence of cutaneous anergy due to overwhelming tuberculosis infection or to an associated immunocompromised condition such as HIV infection, Hodgkin's disease, or sarcoidosis.tu·ber·cu·lin (tū-ber'kyū-lin), 1. A glycerin-broth culture of Mycobacterium tuberculosis evaporated to 1/10 volume at 100°C and filtered; introduced by Robert Koch for the treatment of tuberculosis but now used chiefly for diagnostic tests; originally known as Koch old tuberculin (OT) or Koch original tuberculin 2. One or another of a relatively large number of extracts of Mycobacterium tuberculosis cultures, different from OT and now obsolete. tuberculin (to͝o-bûr′kyə-lĭn, tyo͝o-)n. A sterile liquid containing proteins extracted from cultures of tubercle bacilli and used in tests for tuberculosis.tu·ber·cu·lin (tū-bĕrkyū-lin) A glycerin-broth culture of Mycobacterium tuberculosis evaporated to 1/10 volume at 100°C and filtered; introduced by Robert Koch for the treatment of tuberculosis but now used chiefly for diagnostic tests; originally known as Koch old tuberculin (OT) or Koch original tuberculin. TuberculinA mixture of antigens obtained from the cultured bacteria that cause tuberculosis, Mycobacterium tuberculosis.Mentioned in: Tuberculin Skin Testtu·ber·cu·lin (tū-bĕrkyū-lin) A glycerin-broth culture of Mycobacterium tuberculosis evaporated to 110 volume at 100°C and filtered. tuberculin
Words related to tuberculinnoun a sterile liquid containing a purified protein derivative of the tuberculosis bacteriumRelated Words |