thermogenin

ther·mo·gen·in

(ther'mō-jen'in), A protein found in brown adipose tissue that acts as a thermogenic uncoupling protein of oxidative phosphorylation; it allows thermogenesis in this type of tissue.

UCP1

A gene on chromosome 4q28-q31 that encodes one of the mitochondrial uncoupling proteins (UCP), which belong to the family of mitochondrial anion carrier proteins (MACPs). UCPs separate oxidative phosphorylation from ATP synthesis (the so-called mitochondrial proton leak); facilitate the transfer of anions from the inner to the outer mitochondrial membrane, and protons from the outer to the inner mitochondrial membrane; and reduce the mitochondrial membrane potential in mammalian cells. UCPs contain the 3 homologous protein domains of MACPs; UCP1 is expressed only in brown adipose tissue.

单词	thermogenin
释义	thermogenin ther·mo·gen·in (ther'mō-jen'in), A protein found in brown adipose tissue that acts as a thermogenic uncoupling protein of oxidative phosphorylation; it allows thermogenesis in this type of tissue. UCP1 A gene on chromosome 4q28-q31 that encodes one of the mitochondrial uncoupling proteins (UCP), which belong to the family of mitochondrial anion carrier proteins (MACPs). UCPs separate oxidative phosphorylation from ATP synthesis (the so-called mitochondrial proton leak); facilitate the transfer of anions from the inner to the outer mitochondrial membrane, and protons from the outer to the inner mitochondrial membrane; and reduce the mitochondrial membrane potential in mammalian cells. UCPs contain the 3 homologous protein domains of MACPs; UCP1 is expressed only in brown adipose tissue.
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