reteplase


reteplase

 [ret´ĕ-plās] a recombinant form of activator" >tissue plasminogen activator; used intravenously as a thrombolytic agent in treatment of myocardial infarction.

reteplase

(rĕ-tĕ'plāz), A fibrinolytic agent that works by stimulating production of plasmin.
See also: plasmin.

PLAT

A gene on chromosome 8p12 that encodes tissue plasminogen activator, which converts inactive plasminogen to plasmin by hydrolysing a single Arg-Val bond in plasminogen, thereby playing a key role in tissue remodelling, degradation, cell migration and other cellular events. PLAT directly facilitates neuronal migration.

reteplase

Retavase™ Cardiology A recombinant mutant of alteplase–tPA used to treat acute MI. See Acute myocardial infarction, GUSTO V.

reteplase

A drug that dissolves blood clots. A fibrinolytic drug used in the early stages of a heart attack to try to restore patency to a coronary artery branch that has been blocked by a blood clot. A brand name is Rapilysin.