(1) An insoluble fibrillar protein found in reticular tissue fibers in man and animals. The term has a morphological meaning in that the fibrils of these fibers consist of protein from the collagen group, while glycoproteins form the fibers’ amorphous part.

(2) An antibiotic (synonym hydroxystreptomycin) produced by the actinomycetes Streptomyces griseo-carneus and S. reticuli. It is similar in chemical structure and biological action to streptomycin.

(3) An alkaloid isolated from the tropical plant Annona reticulata.