acanthocyte
enUSNoun | 1. | acanthocyte - an abnormal red blood cell that has thorny projections of protoplasm |
单词 | acanthocyte | |||
释义 | acanthocyteenUS
acanthocyteenUSacanthocyte[ə′kan·thō‚sīt]acanthocyteenUSa·can·tho·cyte(ă-kan'thō-sīt),AcanthocyteA densely stained spheroidal red cell with multiple (usually 5–12), irregularly distributed, thorn-like spicules of variable size, often with drumstick ends.Aetiology Hereditary abetalipoproteinemia* (hereditary acanthocytosis), severe (end stage) liver disease, hepatorenal failure, anorexia nervosa, chronic starvation. A small number of acanthocytes may be seen in severe haemolytic anaemia, especially post splenectomy, haemolytic anaemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration, and rarely also in otherwise normal blood smears (one or two per smear), where they correspond to older, effete red cells approaching their “expiration” date of 120 days. *Accompanied by decreased total serum lipids, phospholipids, cholesterol, vitamin E, vitamin A acanthocyteAcanthrocyte Hematology An RBC with a irregularly spaced, pointed spicules, of varying shape and number–Greek, ακαντηο, spike; acanthocytes are seen in abetalipoproteinemia–hereditary acanthocytosis, as well as in alcoholic cirrhosis with hemolytic anemia, hemolytic anemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration or splenectomy. See Red blood cells.a·can·tho·cyte(ă-kan'thō-sīt)acanthocyteenUS
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