acanthocytosis
enUS| Noun | 1. |  acanthocytosis - the presence of acanthocytes in the blood stream (as in abetalipoproteinemia) |
| 单词 | acanthocytosis | |||
| 释义 | acanthocytosisenUS
acanthocytosisenUSacanthocytosis[ə‚kan·thə‚sī′tō·səs]acanthocytosisenUSacanthocytosis[ah-kan″tho-si-to´sis]a·can·tho·cy·to·sis(ă-kan'thō-sī-tō'sis),acanthocytosis(1) Abetalipoproteinemia, see there.(2) A general term for the presence of acanthocytes in the peripheral blood. Aetiology Hereditary abetalipoproteinemia (hereditary acanthocytosis) accompanied by decreased total serum lipids, phospholipids, cholesterol, vitamin E, vitamin A; severe (end-stage) liver disease; hepatorenal failure; anorexia nervosa; chronic starvation. Small number of acanthocytes may be seen in severe haemolytic anaemia, especially post-splenectomy; haemolytic anaemia due to pyruvate kinase deficiency and intravascular mechanical defects (e.g., cardiac valve protheses, synthetic intravascular grafts and fibrin in DIC) in neonatal hepatitis after heparin administration; and rarely also in otherwise normal blood smears (one or 2 per smear), where they correspond to older, effete red cells approaching the end of their 120-day life-cycle. acanthocytosisa·can·tho·cy·to·sis(ă-kan'thō-sī-tō'sis)acanthocytosisA disorder of red blood cells (erythrocytes) in which the cell surfaces show multiple spine-like projections. This occurs in ABETALIPOPROTEINAEMIA, severe liver disease, vitamin E deficiency (see VITAMINS) and other conditions.acanthocytosisenUS
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