STRA6


STRA6

A gene on chromosome 15q24.1 that encodes a putative high-affinity cell surface receptor for the retinol-retinol-binding protein (RBP/RBP4) complex, which acts by removing retinol and transporting it across the plasma membrane where it is metabolised.
Molecular pathology
Defects in STRA6 cause microphthalmia syndromic type 9 and isolated colobomatous microphthalmia.