silicone-reactive disorder

silicone-reactive disorder

Siliconosis Product liability A proposed autoimmune condition said to be associated with leakage of silicone into surrounding breast and/or systemic penetration thereof Clinical Fatigue, myalgia, arthralgia, synovitis, serositis, sicca syndrome–dry eyes and mouth, dermatitis, alopecia, lymphadenopathy, GI Sx, fever, night sweats, and cognitive dysfunction Diagnosis Clinical features, Hx, microscopy, inductively coupled plasma emission spectroscopy. Cf Silicone testing.