| 释义 |
pyropoikilocytosis py·ro·poi·ki·lo·cy·to·sis (pī'rō-pōy-ki'lō-si-tō-sis), A rare recessive disorder manifested by severe hemolysis, marked poikilocytosis, and a characteristic sensitivity of the red cells to heat-induced fragmentation in vitro; apparently due to a defect in spectrin self-association. Synonym(s): hereditary pyropoikilocytosispyropoikilocytosis (pī″rō-poy″ki-lŏ-sī-tō′sĭs) [ pyro- + poikilocytosis] An inherited form of hemolytic anemia in which cells have defective spectrin in their cytoskeleton, resulting in cellular breakdown during exposure to heat. |