PLCG2
PLCG2
A gene on chromosome 16q24.1 that encodes a phospholipase which mediates production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and plays a key role in transmembrane signalling.Molecular pathology
Defects in PLCG2 cause familial cold autoinflammatory syndrome type 3.