单词 | anthrax meningitis |
释义 | ImmunizationThe anthrax bacillus has been prepared in aerosol form for use in biological warfare. As a result, some American troops have been vaccinated against the disease during their military training with one of several evolving vaccines. The effectiveness of the vaccine in disease prevention remains uncertain. Vaccination is also given to patients affected by active anthrax to prevent relapses.biological warfare; DiagnosisDiagnosis is made by isolating B. anthracis from blood, sputum, or skin lesion cultures. SymptomsSigns and symptoms usually occur within 1 to 7 days after exposure, but can take up to 60 days. Early treatment helps to reduce fatalities. Cutaneous anthrax presents with small, pruritic lesions similar to insect bites that progress to malignant pustules (large, painless boils), vesicles, or skin ulcers with necrotic centers and surrounding brawny edema, usually on an exposed body surface, such as the skin of the hand. Mortality is about 20% from untreated cutaneous anthrax and is less than 1% when treated with an antibiotic (penicillin, doxycycline, ciprofloxacin). GI anthrax involves acute inflammation of the intestinal tract from ingestion of anthrax spores. Symptoms include nausea and vomiting, decreased appetite and fever, progressing to abdominal pain, vomiting blood, and severe to bloody diarrhea. Antibiotic therapy limits mortality to from 25% to 60%. Inhalation anthrax (also called pulmonary anthrax or Woolsorter's disease) is marked by flulike symptoms progressing to fevers, sweats, cough, weakness, and rapidly developing respiratory failure, septic shock, and/or meningitis. Infection of the lungs may be suggested by the rapid onset of respiratory symptoms and chest x-ray or CT findings that may include widening of the mediastinum with hemorrhagic lymph nodes, hilar fullness, and pleural effusion. The disease is often fatal even with the appropriate antibiotic therapy. TreatmentPersons exposed to anthrax (e.g., after its dissemination by bioterrorists) should receive a 60- to 100-day course of preventive therapy with ciprofloxacin, doxycycline, or penicillin G procaine. Individuals who have active infection with anthrax should receive two of the following antibiotics for a 60-day period: aminoglycosides, penicillin G (or amoxicillin), chloramphenicol, ciprofloxacin, doxycycline, imipenem or meropenem, rifampin, tetracycline, or vancomycin. Patients with pleural effusion benefit from drainage of the effusion with a chest tube. Patient careHealth supervision is provided to at-risk employees, along with prompt medical care of all lesions. Terminal disinfection of textile mills contaminated with B. anthracis is supervised, using vaporized formaldehyde or other recommended treatment. All cases of anthrax (in livestock or people) are reported to local health authorities. Isolation procedures (mask, gown, gloves, hand hygiene, and incineration of contaminated materials) are maintained to protect against drainage secretions for the duration of illness in inhalation, GI, and cutaneous anthrax. For patients with inhalation anthrax, vital signs are monitored and respiratory support is provided. For patients with cutaneous anthrax, lesions are kept clean and covered with sterile dressings. Prescribed antibiotics are administered and the patient is assessed for desired and adverse effects. Frequent oral hygiene and skin care are provided. Oral fluid intake and frequent small, nutritious meals are encouraged. anthraxA serious infection of skin, intestine or lungs caused by spores of Bacillus anthracis which can be transmitted to man from infected animals or animal products. There are large and damaging BOILS, severe GASTROENTERITIS and an often fatal PNEUMONIA. Anthrax has been intensively investigated as a bacteriological weapon and concern has been expressed over its suitability as a terrorist weapon. From the Greek anthrax , coal, possibly because of the black centre and the surrounding redness of the skin lesions.anthraxa fever of the spleen in cattle and sheep caused by toxins released from the bacterium Bacillus anthracis. The disease can spread to humans when infected animal products such as wool and bristles are handled, giving rise to malignant skin lesions and pustules.an·thrax(an'thraks)ImmunizationThe anthrax bacillus has been prepared in aerosol form for use in biological warfare. As a result, some American troops have been vaccinated against the disease during their military training with one of several evolving vaccines. The effectiveness of the vaccine in disease prevention remains uncertain. Vaccination is also given to patients affected by active anthrax to prevent relapses.biological warfare; DiagnosisDiagnosis is made by isolating B. anthracis from blood, sputum, or skin lesion cultures. SymptomsSigns and symptoms usually occur within 1 to 7 days after exposure, but can take up to 60 days. Early treatment helps to reduce fatalities. Cutaneous anthrax presents with small, pruritic lesions similar to insect bites that progress to malignant pustules (large, painless boils), vesicles, or skin ulcers with necrotic centers and surrounding brawny edema, usually on an exposed body surface, such as the skin of the hand. Mortality is about 20% from untreated cutaneous anthrax and is less than 1% when treated with an antibiotic (penicillin, doxycycline, ciprofloxacin). GI anthrax involves acute inflammation of the intestinal tract from ingestion of anthrax spores. Symptoms include nausea and vomiting, decreased appetite and fever, progressing to abdominal pain, vomiting blood, and severe to bloody diarrhea. Antibiotic therapy limits mortality to from 25% to 60%. Inhalation anthrax (also called pulmonary anthrax or Woolsorter's disease) is marked by flulike symptoms progressing to fevers, sweats, cough, weakness, and rapidly developing respiratory failure, septic shock, and/or meningitis. Infection of the lungs may be suggested by the rapid onset of respiratory symptoms and chest x-ray or CT findings that may include widening of the mediastinum with hemorrhagic lymph nodes, hilar fullness, and pleural effusion. The disease is often fatal even with the appropriate antibiotic therapy. TreatmentPersons exposed to anthrax (e.g., after its dissemination by bioterrorists) should receive a 60- to 100-day course of preventive therapy with ciprofloxacin, doxycycline, or penicillin G procaine. Individuals who have active infection with anthrax should receive two of the following antibiotics for a 60-day period: aminoglycosides, penicillin G (or amoxicillin), chloramphenicol, ciprofloxacin, doxycycline, imipenem or meropenem, rifampin, tetracycline, or vancomycin. Patients with pleural effusion benefit from drainage of the effusion with a chest tube. Patient careHealth supervision is provided to at-risk employees, along with prompt medical care of all lesions. Terminal disinfection of textile mills contaminated with B. anthracis is supervised, using vaporized formaldehyde or other recommended treatment. All cases of anthrax (in livestock or people) are reported to local health authorities. Isolation procedures (mask, gown, gloves, hand hygiene, and incineration of contaminated materials) are maintained to protect against drainage secretions for the duration of illness in inhalation, GI, and cutaneous anthrax. For patients with inhalation anthrax, vital signs are monitored and respiratory support is provided. For patients with cutaneous anthrax, lesions are kept clean and covered with sterile dressings. Prescribed antibiotics are administered and the patient is assessed for desired and adverse effects. Frequent oral hygiene and skin care are provided. Oral fluid intake and frequent small, nutritious meals are encouraged. anthraxA serious infection of skin, intestine or lungs caused by spores of Bacillus anthracis which can be transmitted to man from infected animals or animal products. There are large and damaging BOILS, severe GASTROENTERITIS and an often fatal PNEUMONIA. Anthrax has been intensively investigated as a bacteriological weapon and concern has been expressed over its suitability as a terrorist weapon. From the Greek anthrax , coal, possibly because of the black centre and the surrounding redness of the skin lesions.anthraxa fever of the spleen in cattle and sheep caused by toxins released from the bacterium Bacillus anthracis. The disease can spread to humans when infected animal products such as wool and bristles are handled, giving rise to malignant skin lesions and pustules.an·thrax(an'thraks) |
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