simethicone
si·meth·i·cone
S5447750 (sĭ-mĕth′ĭ-kōn′)si•meth•i•cone
(saɪˈmɛθ ɪˌkoʊn)n.
单词 | simethicone |
释义 | simethiconesi·meth·i·coneS5447750 (sĭ-mĕth′ĭ-kōn′)si•meth•i•cone(saɪˈmɛθ ɪˌkoʊn)n. simethiconesimethicone[sĭ-meth´ĭ-kōn]simethicone (simeticone (UK))Pharmacologic class: Methylated linear siloxane mixture Therapeutic class: Antiflatulent, antifoam agent Pregnancy risk category NR ActionCauses gas bubbles to coalesce and allows gas to pass through GI tract via belching or passing of flatus. Silicone antifoam spreads on surface of aqueous liquids, forming a film of low surface tension that causes foam bubbles to collapse. AvailabilityCapsules: 95 mg, 125 mg Capsules (liquid-filled): 125 mg, 166 mg Drops: 40 mg/0.6 ml, 40 mg/1 ml, 95 mg/1.425 ml Suspension: 40 mg/0.6 ml, 50 mg/5 ml Tablets: 60 mg, 62.5 mg, 80 mg, 95 mg Tablets (chewable): 40 mg, 80 mg, 125 mg, 150 mg, 166 mg Indications and dosages➣ Excess gas in GI tract after surgery or from air swallowing, dyspepsia, peptic ulcer, or diverticulitis Adults and children older than age 12: 40 to 125 mg P.O. q.i.d. after meals and at bedtime, up to 500 mg/day Children ages 2 to 12: 40 mg P.O. q.i.d., up to 240 mg/day Children younger than age 2: 20 mg P.O. q.i.d. Contraindications• Hypersensitivity to drug • Intestinal perforation or obstruction PrecautionsUse cautiously in: • abdominal pain of unknown cause (especially when accompanied by fever). Administration• Give as needed after meals and at bedtime. Adverse reactionsNone significant InteractionsNone significant Patient monitoring• Monitor GI status to assess drug efficacy. Patient teaching• Tell patient to take after meals and at bedtime as needed. • Caution patient not to take dose higher than indicated on package unless prescriber approves. si·meth·i·cone(si-meth'i-kōn),simethicone(sĭ-mĕth′ĭ-kōn′)si·meth·i·cone(si-meth'i-kōn)simethiconeA silicone-based material with antifoaming properties used in the treatment of flatulence and often incorporated into antacid remedies. |
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