| 释义 |
scleromalacia
scleromalacia (ˌsklɪərəʊməˈleɪʃɪə) n (Medicine) a thinning of the sclera (the eyeball's outer covering) which can occur as a result of rheumatoid arthritisscleromalacia
scleromalacia [skle″ro-mah-la´shah] degeneration (softening) of the sclera, occurring in patients with rheumatoid arthritis.scle·ro·ma·la·ci·a (sklē'rō-mă-lā'shē-ă), Degenerative thinning of the sclera, occurring in people with rheumatoid arthritis and other collagen disorders. [sclero- + G. malakia, a softening] Paget disease of bone type 2 A disorder of bone remodelling (OMIM:602080) that involves the axial skeleton, with lesions of the spine, pelvis and skull.
Molecular pathology
Caused by defects in TNFRSF11A, which encodes a member of the TNF receptor that is essential for RANKL-mediated osteoclastogenesis.scle·ro·ma·la·ci·a (skler'ō-mă-lā'shē-ă) Degenerative thinning of the sclera, occurring in people with rheumatoid arthritis and other collagen disorders. [sclero- + G. malakia, a softening]scleromalacia Softening of the sclera usually as a complication of SCLERITIS complicating RHEUMATOID ARTHRITIS.scleromalacia A bilateral and painless degenerative thinning of the sclera occurring in people with rheumatoid arthritis. In this condition rheumatoid nodules may develop in the sclera and cause perforation (scleromalacia perforans). Syn. necrotizing scleritis without inflammation; scleritis necroticans. |