| 单词 | plk4 |
| 释义 | PLK4PLK4A gene on chromosome 4q27-q28 that encodes a member of the CDC5/Polo subfamily of serine/threonine protein kinases. PLK4 plays a central role in centriole duplication and is also involved in trophoblast differentiation by phosphorylating HAND1, which disrupts the HAND1/MDFIC interaction, leading to HAND1 activation. It also phosphorylates CDC25C and CHEK2. PLK4 is downregulated by p53/TP53. |
| 随便看 |
|
英语词典包含2567994条英英释义在线翻译词条，基本涵盖了全部常用单词的英英翻译及用法，是英语学习的有利工具。