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单词 streptozocin
释义

streptozocin


strep·to·zo·cin

S5873850 (strĕp′tə-zō′sĭn)n. See streptozotocin.

streptozocin


streptozocin

 [strep″to-zo´sin] an antitumor antibiotic derived from Streptomyces achromogenes, now produced synthetically. It contains a nitrosourea group linked to a methyl group and a glucosamine moiety and acts as an alkylating agent to inhibit DNA synthesis, and also as an inhibitor of enzymes involved in gluconeogenesis; used primarily for treatment of islet cell carcinoma of the pancreas and other endocrine tumors including gastrinomas associated with zollinger-ellison syndrome and glucagon-secreting alpha cell tumors of the pancreas.

streptozocin

(strĕp′tə-zō′sĭn)n. See streptozotocin.
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