Spent phase

burned-out phase

A desirable end-stage of polycythemia vera, where hyperproduction of erythrocytes settles down and much of the bone marrow is replaced by reactive fibroblasts, which produce the collagen typical of myelofibrosis.

Spent phase

A late development in PV leading to failure of the bone marrow and severe anemia.Mentioned in: Polycythemia Vera