Weber-Christian disease

[va´ber kris´chan] a disease marked by fever and the formation of crops of tender nodules in the subcutaneous fatty tissues. Called also nodular nonsuppurative panniculitis and Christian-Weber disease.

Web·er-Chris·tian dis·ease

(vā'bĕr kris'chĕn), relapsing febrile nodular nonsuppurative panniculitis of undetermined cause.Synonym(s): relapsing febrile nodular nonsuppurative panniculitis

Weber-Christian syndrome

A rare idiopathic condition that primarily affects adult females; it is a diagnosis of exclusion.

Clinical findings
Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia), hepatosplenomegaly, abdominal pain and episcleritis.

Lab
Nonspecific; leukopenia, increased ESR, rheumatoid factor, cryoglobulinemia.

DiffDx
Erythema induratum, sarcoidosis, post-injection fat necrosis.
Management
Symptomatic relief with corticosteroids, chloroquine, phenylbutazone.

re·lap·sing fe·brile nod·u·lar non·sup·pur·a·tive pan·ni·cu·li·tis

(rē-lap'sing feb'ril nod'yū-lăr non'sŭp'yŭr-ă-tiv pă-nik'yū-lī'tis) Nodular fat necrosis of a varietyof possible causes.
Synonym(s): Christian disease (2) , Christian syndrome, Weber-Christian disease.

Christian,

Henry Asbury, U.S. internist, 1876-1951. Christian disease - (1) Synonym(s): Hand-Schüller-Christian disease; - ; (2) Synonym(s): Weber-Christian diseaseChristian syndrome - Synonym(s): Hand-Schüller-Christian diseaseHand-Schüller-Christian disease - see under HandWeber-Christian disease - see under Weber, Frederick Parkes

Weber,

Frederick Parkes, English physician, 1863-1962. Klippel-Trenaunay-Weber syndrome - see under KlippelRendu-Osler-Weber syndrome - see under RenduSturge-Kalischer-Weber syndrome - Synonym(s): Sturge-Weber syndromeSturge-Weber disease - Synonym(s): Sturge-Weber syndromeSturge-Weber syndrome - see under SturgeWeber-Christian disease - a group of conditions with recurrent subcutaneous nodules, with or without fever or suppuration, followed by depression of the overlying skin. Synonym(s): Christian disease (2); nodular nonsuppurative panniculitisWeber-Cockayne syndrome - epidermolysis bullosa of the hands and feet.

单词	weber-christian disease
释义	DictionarySeedisease Weber-Christian disease Weber-Christian disease [′vā·bər ′kris·chən di‚zēz] (medicine) Febrile, relapsing, nodular nonsuppurative panniculitis. Weber-Christian disease Weber-Christian disease [va´ber kris´chan] a disease marked by fever and the formation of crops of tender nodules in the subcutaneous fatty tissues. Called also nodular nonsuppurative panniculitis and Christian-Weber disease. Web·er-Chris·tian dis·ease (vā'bĕr kris'chĕn), relapsing febrile nodular nonsuppurative panniculitis of undetermined cause.Synonym(s): relapsing febrile nodular nonsuppurative panniculitis Weber-Christian syndrome A rare idiopathic condition that primarily affects adult females; it is a diagnosis of exclusion. Clinical findings Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia), hepatosplenomegaly, abdominal pain and episcleritis. Lab Nonspecific; leukopenia, increased ESR, rheumatoid factor, cryoglobulinemia. DiffDx Erythema induratum, sarcoidosis, post-injection fat necrosis. Management Symptomatic relief with corticosteroids, chloroquine, phenylbutazone. re·lap·sing fe·brile nod·u·lar non·sup·pur·a·tive pan·ni·cu·li·tis (rē-lap'sing feb'ril nod'yū-lăr non'sŭp'yŭr-ă-tiv pă-nik'yū-lī'tis) Nodular fat necrosis of a varietyof possible causes. Synonym(s): Christian disease (2) , Christian syndrome, Weber-Christian disease. Christian, Henry Asbury, U.S. internist, 1876-1951. Christian disease - (1) Synonym(s): Hand-Schüller-Christian disease; - ; (2) Synonym(s): Weber-Christian diseaseChristian syndrome - Synonym(s): Hand-Schüller-Christian diseaseHand-Schüller-Christian disease - see under HandWeber-Christian disease - see under Weber, Frederick Parkes Weber, Frederick Parkes, English physician, 1863-1962. Klippel-Trenaunay-Weber syndrome - see under KlippelRendu-Osler-Weber syndrome - see under RenduSturge-Kalischer-Weber syndrome - Synonym(s): Sturge-Weber syndromeSturge-Weber disease - Synonym(s): Sturge-Weber syndromeSturge-Weber syndrome - see under SturgeWeber-Christian disease - a group of conditions with recurrent subcutaneous nodules, with or without fever or suppuration, followed by depression of the overlying skin. Synonym(s): Christian disease (2); nodular nonsuppurative panniculitisWeber-Cockayne syndrome - epidermolysis bullosa of the hands and feet.
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