| 释义 |
West African sleeping sickness Gam·bi·an try·pan·o·so·mi·a·sisa chronic disease of humans caused by Trypanosoma brucei gambiense in northern and sub-Saharan Africa from Senegal east to Sudan and Uganda; characterized by splenomegaly, drowsiness, an uncontrollable urge to sleep, and the development of psychotic changes; basal ganglia and cerebellar involvement commonly lead to chorea and athetosis; the terminal phase of the disease is characterized by wasting, anorexia, and emaciation that gradually leads to coma and death, usually from intercurrent infection. Synonym(s): chronic African sleeping sickness, chronic trypanosomiasis, gambiense sleeping sickness, West African sleeping sickness, West African trypanosomiasis |