| 释义 |
Wilson's disease
Wil·son disease W5173200 (wĭl′sən) or Wil·son's disease (-sənz)n. A rare genetic disease caused by a defect in copper metabolism, resulting in the accumulation of copper in the liver, brain, kidneys, and cornea and causing neurological symptoms and liver disease.
[After Samuel Alexander Kinnier Wilson (1877-1937), British neurologist.]Wil′son's disease`
n. a rare hereditary disease marked by copper accumulation in the brain and liver, leading to neurological damage and kidney malfunction. (after Samuel Alexander Kinnier Wilson (1878–1936), British neurologist, who described it in 1912] Thesaurus| Noun | 1. |  Wilson's disease - a rare inherited disorder of copper metabolism; copper accumulates in the liver and then in the red blood cells and brainhepatolenticular degenerationcongenital disease, genetic abnormality, genetic defect, genetic disease, genetic disorder, hereditary condition, hereditary disease, inherited disease, inherited disorder - a disease or disorder that is inherited genetically |
TranslationsWilson's disease
Wilson's disease[′wil·sənz di‚zēz] (medicine) A hereditary disease of ceruloplasmin formation transmitted as an autosomal recessive and characterized by decreased serum ceruloplasmin and copper values, and increased excretion of copper in the urine. Also known as hepatolenticular degeneration. Wilson's disease
Wilson's disease [wil´sunz] a rare progressive disease, inherited as an autosomal recessive trait and due to a defect in metabolism of copper, with accumulation of copper in the liver, brain, kidney, cornea, and other tissues. Characteristics include cirrhosis of the liver and degenerative changes in the brain, particularly the basal ganglia. Liver disease is the most likely manifestation in children; neurologic disease is most common in young adults. The characteristic ophthalmic feature is a pigmented ring (ring" >Kayser-Fleischer ring) at the outer margin of the cornea. Called also hepatolenticular degeneration.Wilson's disease Neurology An AR disorder of copper metabolism characterized by accumulation of copper in the brain, liver, and other organs Clinical Cirrhosis, degeneration of basal ganglia and neurologic deterioration with involuntary movement, tremors, muscular rigidity, spastic contractures, psychiatric defects, dysphagia, Kayser-Fleischer ring. See Ceruloplasmin, Copper. Wilson's disease A rare genetic disorder in which copper accumulates in the body, especially in the liver and brain, causing CIRRHOSIS and brain damage. There are behaviour abnormalities and personality changes, writhing movements of the limbs (athetoid movements), muscle rigidity and shortening, dementia and, in untreated cases, death. If diagnosed early, often by the observation of a ring of greenish-brown discoloration in each cornea (KAYSER-FLEISCHER RING), the condition may be controlled with a diet low in copper and the use of the drug d-penicillamine, which binds copper into a form which is excreted in the urine. Also known as hepato-lenticular degeneration. (Samuel Alexander Kinnier Wilson, 1878–1937, American-born English neurologist).Wilson's diseaseAn inborn defect of copper metabolism in which free copper may be deposited in a variety of areas of the body. Deposits in the brain can cause tremor and other symptoms of Parkinson's disease.Mentioned in: Movement Disorders, Pseudogout, Tremors, Uric Acid TestsPatient discussion about Wilson's diseaseQ. Hi this is Wilson; I have a daughter, who is 5. She has frequent nose bleeds when she is behaving badly. Hi this is Bell; I have a daughter, who is 5. She has frequent nose bleeds when she is behaving badly. She has been screened by her school for ADHD and I haven’t had a chance to consult a doctor for her screening and exam for ADHD. I thought that her nose bleeds cause due to her behavior? I need help.A. I don’t have an idea about this. But I think that you should first discuss these issues with your doctor. Also mention to the doctor if she has any problems with sleeping, like only sleeping 6 hours a night. Try with occupational Therapists which help children and adults with small motor issues like handwriting and also with sensory issues like learning how to calm down. Early intervention is always best. More discussions about Wilson's diseaseWilson's disease
Related to Wilson's disease: Huntington's diseaseSynonyms for Wilson's diseasenoun a rare inherited disorder of copper metabolismSynonyms- hepatolenticular degeneration
Related Words- congenital disease
- genetic abnormality
- genetic defect
- genetic disease
- genetic disorder
- hereditary condition
- hereditary disease
- inherited disease
- inherited disorder
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