benign giant lymph node hyperplasia

be·nign giant lymph node hy·per·pla·si·a

solitary masses of lymphoid tissue containing concentric perivascular aggregates of lymphocytes, occurring usually in the mediastinum or hilar region of young adults; similar changes have been reported outside the mediastinum and, if associated with interfollicular sheets of plasma cells, may progress to lymphoma or plasmacytoma. Synonym(s): angiofollicular mediastinal lymph node hyperplasia, Castleman disease

Castleman,

Benjamin, U.S. pathologist, 1906-1982. Castleman disease - solitary masses of lymphoid tissue containing concentric perivascular aggregates of lymphocytes. Synonym(s): benign giant lymph node hyperplasia; Castleman tumorCastleman tumor - Synonym(s): Castleman disease