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DictionarySeecellaccessory cell
accessory cell[ak′ses·ə·rē ‚sel] (botany) A morphologically distinct epidermal cell adjacent to, and apparently functionally associated with, guard cells on the leaves of many plants. (immunology) Any nonlymphocytic cell that helps in the induction of the immune response by presenting antigen to a helper T lymphocyte. accessory cell
an·ti·gen-·pre·sent·ing cells (APC), cells that process protein antigens into peptides and present them on their surface in a form that can be recognized by lymphocytes. APCs include Langerhans cells, dendritic cells, macrophages, B cells, and, in humans, activated T cells. Synonym(s): accessory cellaccessory cell A macrophage that aids in immune recognition by binding circulating antigens, processing them and presenting them on cell surfaces so that the immune recognition cascade can proceed, which in addition secrete a broad palette of cytokines and biological response modifiers.
Binding of an antigen to a self-cell is essential for T-cell response to an antigen, as the T-cell receptor requires a self-MHC class-II molecule with a bound foreign antigen before it can respond to an antigen.an·ti·gen-pre·sent·ing cells (APC) (an'ti-jen-prĕ-zent'ing selz) Cells that process protein antigens into peptides and present them on their surface in a form that can be recognized by lymphocytes. APCs include Langerhans cells, dendritic cells, macrophages, B cells, and in humans, activated T cells.
Synonym(s): accessory cell. accessory cellA monocyte or macrophage that participates in the immune response. See: antigen-presenting cell; macrophageSee also: cellLegalSeeCell |