anticholinesterase

enUK

an·ti·cho·li·nes·ter·ase

A0336000 (ăn′tē-kō′lə-nĕs′tə-rās′, -rāz′, ăn′tī-)n. A substance that inhibits the activity of a cholinesterase, especially acetylcholinesterase.

anticholinesterase

(ˌæntɪˌkɒləˈnɛstəˌreɪz) n (Biochemistry) any of a group of substances that inhibit the action of cholinesterase

an•ti•cho•lin•es•ter•ase

(ˌæn tiˌkoʊ ləˈnɛs təˌreɪs, -ˌreɪz, -ˌkɒl ə-, ˌæn taɪ-)

n. an enzyme or drug that blocks the action of acetylcholinesterase, thereby increasing the stimulating effect of acetylcholine on the muscles. [1950–55]

Thesaurus

Noun

anticholinesterase - a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effectmedicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of diseaseneostigmine, Prostigmin - a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravis

anticholinesterase

enUK

anticholinesterase

[an″te-, an″ti-ko″lin-es´ter-ās] an agent that inhibits acetylcholinesterase, the enzyme that breaks down acetylcholine at junctions of cholinergic nerve endings and effector organs or postsynaptic neurons; this permits the accumulation of acetylcholine and increases the stimulation of receptors" >cholinergic receptors in the central and peripheral nervous systems. Called also cholinesterase inhibitor.
Organophosphate insecticides and chemical-warfare agents (nerve gases) are highly toxic “irreversible” anticholinesterases; “reversible” anticholinesterases such as neostigmine and physostigmine are used for treatment of myasthenia gravis, glaucoma, and smooth muscle atony of the gastrointestinal tract and for termination of the effect of nondepolarizing neuromuscular blocking agents and cholinergic blocking agents. Poisoning by anticholinesterases is treated with atropine and the cholinesterase reactivator pralidoxime.

an·ti·cho·lin·es·ter·ase

(an'tē-kō-lin-es'ter-ās), One of the drugs that inhibit or inactivate acetylcholinesterase, either reversibly (for example, physostigmine) or irreversibly (for example, tetraethyl pyrophosphate).

anticholinesterase

(ăn′tē-kō′lə-nĕs′tə-rās′, -rāz′, ăn′tī-)n. A substance that inhibits the activity of a cholinesterase, especially acetylcholinesterase.

anticholinesterase

Pharmacology An agent–eg, certain nerve gases, which blocks nerve impulses by inhibiting anticholinesterase Examples Insecticides–eg, parathion, and nerve gas agents–eg, sarin, soman, tabun; AChEs can be reversible or irreversible Action Eyes–hyperemia and pupillary constriction, GI tract—↑ GI contractions and secretion of gastric acid

an·ti·cho·lin·es·ter·ase

(AChE) (an'tē-kō-lin-es'tĕr-ās) Any compound that inhibits or inactivates acetylcholinesterase, either reversibly (as e.g., physostigmine and other carbamates) or irreversibly (e.g., tetraethyl pyrophosphate and other organophosphorous compounds, including nerve agents).

anticholinesterase

Any substance opposing the action of the enzyme cholinesterase, which breaks down the NEUROTRANSMITTER acetylcholine, releasing the inactive choline for further synthesis to acetylcholine. An anticholinesterase agent thus potentiates the action of acetylcholine, a major neurotransmitter carrying nerve impulses across synapses and from nerves to muscles. Continued action causes serious effects. A number of organophosphorus insecticides and some nerve gases are anticholinesterases. Poisoning produces nausea, vomiting, sweating, salivation, restlessness, tightness of the chest, blurred vision, diarrhoea convulsions and death.

an·ti·cho·lin·es·ter·ase

(an'tē-kō-lin-es'tĕr-ās) A drug that inhibits or inactivates acetylcholinesterase, either reversibly (e.g., physostigmine) or irreversibly (e.g., tetraethyl pyrophosphate).

anticholinesterase

an·ti·cho·li·nes·ter·ase

anticholinesterase

an•ti•cho•lin•es•ter•ase

anticholinesterase

anticholinesterase

anticholinesterase

anticholinesterase

an·ti·cho·lin·es·ter·ase

anticholinesterase

anticholinesterase

an·ti·cho·lin·es·ter·ase

anticholinesterase

an·ti·cho·lin·es·ter·ase

anticholinesterase

Words related to anticholinesterase

noun a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect

Related Words