anti-sperm antibody

Any of a group of antibodies produced against four distinct components of the sperm. While ASAs are linked to infertility, their presence is not associated with a particular disease; ASAs may be found in the circulation, either free or as immune complexes, in seminal fluid and/or attached to the sperm surface.

Ref range/normal
IgA, IgG, IgM < 15% binding.

Low titres (< 1:8 of ASAs) are present in 90% of prepubertal boys and are of no significance; up to 50% of infertile women have anti-sperm antibody titres of ≥ 1:16, most commonly as IgG or IgA anti-sperm (tail-immobilising) antibodies, while male homosexuals tend to develop IgM anti-sperm (head-agglutinating) antibodies.

Specimen
Serum, semen IgE.

Method
ELISA.

anti-sperm antibody

Any of a group of antibodies produced against 4 distinct components of the sperm; although ASAs are linked to infertility, their presence is not associated with a particular disease; ASAs may be found in the circulation, either free or as immune complexes, in seminal fluid and/or attached to the sperm surface Ref range/normal IgA, IgG, IgM < 15% binding

单词	anti-sperm antibody
释义	anti-sperm antibody anti-sperm antibody Any of a group of antibodies produced against four distinct components of the sperm. While ASAs are linked to infertility, their presence is not associated with a particular disease; ASAs may be found in the circulation, either free or as immune complexes, in seminal fluid and/or attached to the sperm surface. Ref range/normal IgA, IgG, IgM < 15% binding. Low titres (< 1:8 of ASAs) are present in 90% of prepubertal boys and are of no significance; up to 50% of infertile women have anti-sperm antibody titres of ≥ 1:16, most commonly as IgG or IgA anti-sperm (tail-immobilising) antibodies, while male homosexuals tend to develop IgM anti-sperm (head-agglutinating) antibodies. Specimen Serum, semen IgE. Method ELISA. anti-sperm antibody Any of a group of antibodies produced against 4 distinct components of the sperm; although ASAs are linked to infertility, their presence is not associated with a particular disease; ASAs may be found in the circulation, either free or as immune complexes, in seminal fluid and/or attached to the sperm surface Ref range/normal IgA, IgG, IgM < 15% binding EncyclopediaSeeÁsa
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