单词 | zileuton |
释义 | zileutonzi·leu·tonZ0015650 (zī-lo͞o′tn)zileutonzileuton[zi-loo´ton]zileuton(zī-lo͞o′tn)A64077An experimental therapeutic which inhibits the 5-lipoxygenase pathway of arachidonic acid metabolism, which attenuates the bronchoconstriction response in asthmatics to cold air and allergen-induced nasal constriction, a response attributed to the eicosanoids produced by 5-lipoxygenase—e.g., sulfidopeptide leukotrienes, 5-HETE, and leukotriene B4.zileutonZyflo® Clinical medicine An inhibitor of 5-lipoxygenase, an enzyme central to leukotriene synthesis, which mediates inflammatory responses Indications Asthma. See Asthma.Zileuton (Zyflo) |
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