beta2 microglobulin

beta2 microglobulin

(mi?kro-glob'u-lin),

ß2-m

A polypeptide that is one of the class I major histocompatibility markers on cell surfaces; it is grouped into chains of low molecular weight called light chains. The ß2-m chain may be affected by the nef gene in HIV, preventing CD8+ T lymphocytes from recognizing the virus. See: acquired immunodeficiency syndrome; major histocompatibility complex