beta-adrenergic blocking agent

n. See beta-blocker.

Thesaurus

Noun

beta-adrenergic blocking agent - any of various drugs used in treating hypertension or arrhythmia; decreases force and rate of heart contractions by blocking beta-adrenergic receptors of the autonomic nervous systembeta blocker, beta-adrenergic blocker, beta-blocking agentacebutolol, Sectral - an oral beta blocker (trade name Sectral) used in treating hypertensionatenolol, Tenormin - an oral beta blocker (trade name Tenormin) used in treating hypertension and angina; has adverse side effects (depression and exacerbation of congestive heart failure etc.)blocking agent, blocker - a class of drugs that inhibit (block) some biological processcarvedilol - beta blocker that can reduce the progression of heart failure in individuals whose disease is not advancedBrevibloc, esmolol - intravenous beta blocker (trade name Brevibloc) that acts for only a short time; used primarily for cardiac arrhythmiasLopressor, metoprolol - beta blocker (trade name Lopressor) used in treating hypertension and angina and arrhythmia and acute myocardial infarction; has adverse side effects (depression and exacerbation of congestive heart failure etc.)Corgard, nadolol - a beta-adrenergic blocking agent (trade name Corgard) that is used to treat hypertension and anginapindolol, Visken - an oral beta blocker (trade name Visken) used in treating hypertensionInderal, propanolol - the first beta blocker (trade name Inderal) used in treating hypertension and angina pectoris and essential tremorBlocadren, timolol - a beta blocker (trade name Blocadren) administered after heart attacks

beta-adrenergic blocking agent

beta

[ba´tah] second letter of the Greek alphabet, β; used to denote the second position in a classification system. Often used in names of chemical compounds to distinguish one of two or more isomers or to indicate the position of substituent atoms or groups in certain compounds. Also used to distinguish types of radioactive decay; brain rhythms or waves; adrenergic receptors; secretory cells of the various organs of the body that stain with basic dyes, such as the beta cells of the pancreas; and the type of hemolytic streptococci that produce a zone of decolorization when grown on blood media.beta-adrenergic blocking agent (beta-blocker) any of a group of drugs that block the action of epinephrine at beta-adrenergic receptors on cells of effector organs. There are two types of these receptors: β₁-receptors in the myocardium and β₂-receptors in the bronchial and vascular smooth muscles. The principal effects of beta-adrenergic stimulation are increased heart rate and contractility, vasodilation of the arterioles that supply the skeletal muscles, and relaxation of bronchial muscles.
Because of their effects on the heart, these agents are used to treat angina pectoris, hypertension, and cardiac arrhythmias. And, because they decrease the workload of the heart, they are effective in reducing the long-term risk of mortality and reinfarction after recovery from the acute phase of a myocardial infarction. They are an important adjunct in treatment of heart failure and are also used for prophylaxis of migraine.
Nonselective beta-adrenergic blocking agents affect both types of receptors and can produce bronchospasm in patients with asthma or chronic obstructive pulmonary disease. If such patients need one of these drugs, they should be given a cardioselective one that preferentially blocks the β₁-receptors in the heart.
Nonselective agents include propranolol" >propranolol (Inderal), used for treatment of angina, hypertension, arrhythmias, and migraine and for prophylaxis after the acute phase of a myocardial infarction; nadolol" >nadolol (Corgard), used for treatment of angina and hypertension; and timolol" >timolol, used as an ophthalmic preparation (Timoptic) for treatment of glaucoma and as an oral preparation (Blocadren) for treatment of hypertension and for prophylaxis after the acute phase of a myocardial infarction. Cardioselective beta-adrenergic blocking agents are used for treatment of hypertension and include atenolol" >atenolol (Tenormin) and metoprolol" >metoprolol (Lopressor).beta particles negatively charged particles emitted by radioactive elements, the result of disintegration of neutrons; their source is the unstable atoms of radioactive metals such as radium and uranium. There are three general types of emissions from radioactive substances: alpha and beta particles and gamma rays. Beta particles are less penetrating than gamma rays and may be used to treat certain conditions on or near the surface of the body. See also radiation and radiation therapy.

β-ad·re·ner·gic block·ing a·gent

a class of drugs that competes with β-adrenergic agonists for available receptor sites; some compete for both β₁ and β₂ receptors (for example, propranolol) whereas others are primarily either β₁ (for example, metoprolol) or β₂ blockers; used in the treatment of a variety of cardiovascular diseases for which β-adrenergic blockade is desirable. Synonym(s): β-adrenergic receptor blocking agent, β-adrenoreceptor antagonist, beta-blocker

beta-blocker

Any of a class of agents that blocks 1 and/or 2 adrenergic receptors in the nervous system, modulating cardiac functions, respiratory functions and the dilation of blood vessels.

Effect
Slowed heart rate, lowered blood pressure, reduced anxiety.

Indications
• General medicine
Angina, arrhythmias, hypertension, mitral valve prolapse, tachycardia, migraine, etc.
• Psychiatry
Aggression and violence, anxiety-related tremors and lithium-induced tremors, neuroleptic-induced akathisia, social phobias, panic states and alcohol withdrawal.
Examples
Carvedilol, sotalol, metoprolol, propranolol, atenolol, esmolol.

beta-blocker

A drug that blocks or reduces the action of neurotransmitters on beta-adrenergic receptors. It reduces secretion of aqueous humour and consequently intraocular pressure and it is used in the treatment of glaucoma. Common beta-blockers include timolol maleate, betaxolol hydrochloride, carteolol hydrochloride, levobunolol hydrochloride and metipranolol. Timolol is often used together with another agent (combination drugs), e.g. timolol and brimonidine, timolol and dorzolamide, timolol and latanoprost. Syn. beta-adrenergic antagonist; beta-adrenergic blocking agent. See adrenergic receptors; miotics; sympatholytic drugs.

beta-adrenergic blocking agent