BARI 2D

BARI 2D

Bypass Angioplasty Revascularization Investigation 2D. A multicentre, multinational trial comparing the mortality of type-2 diabetics with stable coronary artery disease, managing myocardial ischemia either by immediate revascularisation plus intense medical therapy or by intense medical therapy alone, and management of the diabetes by an insulin-sensitising or by an insulin-providing strategy.
Conclusion
There were similar rates of mortality and major cardiovascular events for prompt revascularisation vs delayed or no revascularisation, and insulin sensitisation vs insulin provision. In high-risk patients selected for CABG, prompt revascularisation reduces major cardiovascular events compared with delayed or no revascularisation, a finding that doesn’t hold for low-risk patients selected for percutaneous coronary intervention.