| 释义 |
DictionarySeeM1EncyclopediaSeeL2FAB classification
FAB classification (French-American-British) a classification of leukemia" >acute leukemia produced by a three-nation joint collaboration; leukemia" >acute lymphoblastic leukemia is subdivided into three types and leukemia" >acute myelogenous leukemia is subdivided into eight types. French-American-British (FAB) classification of acute leukemias: the myeloid leukemias are divided into eight types (M0-7) and the lymphoblastic leukemias into three (L1-3). From Hoffbrand and Pettit, 2000.FAB classificationFrench-American-British classification of acute leukemias based on the study of microscopic features and cytochemistry of blast cells; it subdivides acute myelogenous leukemias into 8 groups (M0-M7) and acute lymphoblastic leukemias into 3 groups (L1-L3); widely used in clinical practice. Synonym(s): French-American-British classificationFAB classification French-American-British classification of acute leukemia Hematology A schema that divides acute leukemias into lymphoid–ALL or myeloid–AML cell lines; of childhood ALL, 70% are predominantly L1, 27% are L2, and 3% or less are L3 or Burkitt cell type, in adults with ALL, 30% are L1, 65% are L2, and 5% are L3 FAB classification, acute leukemias Acute lymphocytic leukemia (ALL) L1 Small monotonous lymphocytes L2 Mixed L1- and L3-type lymphocytes L3 Large homogeneous blast cells Acute myeloid leukemia (AML) M1 Myeloblasts without maturation M2 Myeloblasts with maturation (best AML prognosis) M3 Hypergranular promyelocytic leukemia (faggot cells) M3V Variant, microgranular promyelocytic leukemia M4 Myelomonocytic leukocytes M5 Monocytic, subtype a. Poorly differentiated monocytic leukemia b. Well differentiated monocytic leukemia M6 Erythroleukemia/DiGuglielmo syndrome M7 Megakaryocytic leukemia Pleomorphic undifferentiated cells with cytoplasmic blebs; myelofibrosis or ↑ BM reticulin; positive for platelet peroxidase antifactor VIII |