单词 | acid-sensitive ion channels |
释义 | acid-sensitive ion channelsacid-sensitive ion channelsVoltage-insensitive protein cell-membrane sub-units which are activated and open when the pH falls below about 7.0. The activation of neuronal acid-sensitive channels can lead to neuronal death by excessive loading of the neurons by calcium. Many other calcium-permeable channels are inhibited as pH falls. Ischaemic tissue such as the surroundings of brain infarcts are at reduced pH. |
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