corneal dystrophy, lattice type 3A

An autosomal dominant (OMIM:608471) form of corneal dystrophy characterised by wispy, greyish, cotton-like threads limited to a zone between the centre of the cornea and the periphery, with very slowly progressive loss of vision that develops in older elders aged 70 to 90.
Molecular pathology
Has been linked to defects of TGFBI, which encodes an RGD protein that binds to type-I, -II and -IV collagens and plays a role in cell–collagen interactions.

单词	corneal dystrophy, lattice type 3a
释义	corneal dystrophy, lattice type 3A corneal dystrophy, lattice type 3A An autosomal dominant (OMIM:608471) form of corneal dystrophy characterised by wispy, greyish, cotton-like threads limited to a zone between the centre of the cornea and the periphery, with very slowly progressive loss of vision that develops in older elders aged 70 to 90. Molecular pathology Has been linked to defects of TGFBI, which encodes an RGD protein that binds to type-I, -II and -IV collagens and plays a role in cell–collagen interactions.
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