| 释义 |
frameshift mutation
frame·shift mutation (frām′shĭft′)n. A mutation in a DNA chain that occurs when the number of nucleotides inserted or deleted is not a multiple of three, so that every codon beyond the point of insertion or deletion is read incorrectly during translation.Translationsframeshift mutation
frameshift mutation[¦frām‚shift myü′tā·shən] (genetics) The addition or deletion of nucleotides to anexon in numbers other than three, which shifts the translation reading frame so a new set of codons beyond the point of abnormality in the messenger ribonucleic acid is read. Also known as phase-shift mutation. frameshift mutation
read·ing-·frame·shift mu·ta·tiona mutation that results from insertion or deletion of a single nucleotide into, or from, the normal DNA sequence; because the genetic code is read three nucleotides at a time, all nucleotide triplets distal to the mutation will be one step out of phase and misread, and hence translated as different amino acids. Synonym(s): addition mutation, addition-deletion mutation, deletion mutation, frameshift mutationframeshift mutation (frām′shĭft′)n. A mutation in a DNA chain that occurs when the number of nucleotides inserted or deleted is not a multiple of three, so that every codon beyond the point of insertion or deletion is read incorrectly during translation.frameshift mutationThe deletion or insertion of one or two DNA nucleotides that alters the transcription of each subsequent triplet.See also: mutationLegalSeeMutationThesaurusSeemutation |