| 单词 | cystic fibrosis transmembrane conductance regulator |
| 释义 | cystic fibrosis transmembrane conductance regulatorcystic fibrosis transmembrane conductance regulator[¦sis·tik fī¦brō·səs tranz¦mem‚brān kən′dək·təns ‚reg·yə‚lād·ər]cystic fibrosis transmembrane conductance regulatorcystic fibrosis transmembrane conductance regulatorSee also: cystic fibrosis. CFTRA gene on chromosome 7q31.2 that encodes cystic fibrosis transmembrane conductance regulator, a protein of the MRP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes and many of which are involved in multidrug resistance. CFTR functions as a chloride channel and controls the regulation of other transport pathways.Molecular pathology CFTR mutations cause cystic fibrosis and bilateral aplasia of the vas deferens. See CFTCR |
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