cytotoxic reaction

cy·to·tox·ic re·ac·tion

an immunologic (that is, allergic) reaction in which noncytotropic IgG or IgM antibody combines with specific antigen on cell surfaces; the resulting complex initiates the activation of complement, which causes cell lysis or other damage, or which, in the absence of complement, may lead to phagocytosis or enhance T-lymphocyte involvement leading to cellular cytotoxicity.

cy·to·tox·ic re·ac·tion

(sī'tō-tok'sik rē-ak'shŭn) An immunologic (allergic) reaction in which noncytotropic IgG or IgM antibody combines with a specific antigen on cell surfaces; the resulting complex initiates the activation of complement, which causes cell lysis or other damage, or, in the absence of complement, may lead to phagocytosis or may enhance T-lymphocyte involvement.