antiidiotype antibody

an·ti·id·i·o·type an·ti·bod·y

an antiantibody, the activity of which is directed specifically against the antigenic determinants (idiotope) of a particular immunoglobulin (antibody) molecule. In an idiotype-antiidiotype network, the antigen-combining region on one antibody molecule acts as the antigen for an antiidiotypic antibody. Synonym(s): idiotypic antibody

an·ti·id·i·o·type an·ti·bod·y, an·ti·id·i·o·type au·to·an·ti·bod·y

(an'tē-id'ē-ō-tīp an'ti-bod-ē, aw'tō-an'ti-bod-ē) An antiantibody, the activity of which is directed specifically against the antigenic determinants (idiotope) of a particular immunoglobulin (antibody) molecule.